Detalhe da pesquisa
1.
PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia.
Blood
; 139(9): 1340-1358, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34788382
2.
DNA Origami Nanostructures Elicit Dose-Dependent Immunogenicity and Are Nontoxic up to High Doses In Vivo.
Small
; 18(26): e2108063, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35633287
3.
Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells.
J Immunol
; 202(9): 2806-2816, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30910862
4.
VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.
Leukemia
; 37(2): 326-338, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36376377
5.
Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Nat Commun
; 14(1): 97, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609611
6.
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor-mediated synergistic antileukemic actions.
Sci Adv
; 8(37): eabp9005, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112677
7.
Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation.
J Hematol Oncol
; 14(1): 101, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187548
8.
Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia.
Nat Commun
; 12(1): 6338, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34732719
9.
Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol
; 14(1): 17, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33451349
10.
Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition.
Clin Cancer Res
; 27(8): 2352-2366, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33542077
11.
Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia.
J Hematol Oncol
; 13(1): 139, 2020 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33076970
12.
Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia.
Blood Adv
; 3(3): 242-255, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30692102
13.
BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Cancer Discov
; 8(4): 458-477, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386193
14.
Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells.
Leukemia
; 34(6): 1679-1683, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980730