Detalhe da pesquisa
1.
Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study.
BMC Med
; 21(1): 246, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37408015
2.
A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability-nonexchangeability method.
Stat Med
; 42(24): 4392-4417, 2023 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37614070
3.
How to design a dose-finding study using the continual reassessment method.
BMC Med Res Methodol
; 19(1): 18, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30658575
4.
Adaptive designs in clinical trials: why use them, and how to run and report them.
BMC Med
; 16(1): 29, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490655
5.
SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol.
BMJ Open
; 13(3): e068173, 2023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36990492
6.
Adaptive Designs: Results of 2016 Survey on Perception and Use.
Ther Innov Regul Sci
; 54(1): 42-54, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32008237
7.
Clinical trial protocol for TRANSFORM-UK: A therapeutic open-label study of tocilizumab in the treatment of pulmonary arterial hypertension.
Pulm Circ
; 8(1): 2045893217735820, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28956500
8.
A computational framework for complex disease stratification from multiple large-scale datasets.
BMC Syst Biol
; 12(1): 60, 2018 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843806
9.
The need for reporting guidelines for early phase dose-finding trials: Dose-Finding CONSORT Extension.
Nat Med
; 28(1): 6-7, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34992264
10.
Early phase clinical trials extension to guidelines for the content of statistical analysis plans.
BMJ
; 376: e068177, 2022 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35131744
11.
The combined use of ibutilide as an active control with intensive electrocardiographic sampling and signal averaging as a sensitive method to assess the effects of tadalafil on the human QT interval.
J Am Coll Cardiol
; 46(4): 678-87, 2005 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098435
12.
Effects of tadalafil on myocardial blood flow in patients with coronary artery disease.
Coron Artery Dis
; 17(6): 493-9, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16905960
13.
Detecting Data Quality Issues in Clinical Trials: Current Practices and Recommendations.
Ther Innov Regul Sci
; 50(1): 15-21, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30236017
14.
Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo.
Clin Pharmacol Ther
; 77(1): 63-75, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15637532
15.
Adaptive Design: Results of 2012 Survey on Perception and Use.
Ther Innov Regul Sci
; 48(4): 473-481, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30235570
16.
Effects of gender, age, diabetes mellitus and renal and hepatic impairment on tadalafil pharmacokinetics.
Br J Clin Pharmacol
; 63(1): 24-35, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16869816
17.
Tadalafil pharmacokinetics in healthy subjects.
Br J Clin Pharmacol
; 61(3): 280-8, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16487221
18.
The effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease.
Br J Clin Pharmacol
; 60(5): 459-68, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16236035
19.
Interaction between the phosphodiesterase 5 inhibitor, tadalafil and 2 alpha-blockers, doxazosin and tamsulosin in healthy normotensive men.
J Urol
; 172(5 Pt 1): 1935-40, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15540759