Detalhe da pesquisa
1.
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
Brain Behav Immun
; 80: 439-451, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980952
2.
Activation of σ1 and σ2 receptors by afobazole increases glial cell survival and prevents glial cell activation and nitrosative stress after ischemic stroke.
J Neurochem
; 139(3): 497-509, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27488244
3.
Lymphocyte-Activation Gene 3 Facilitates Pathological Tau Neuron-to-Neuron Transmission.
Adv Sci (Weinh)
; 11(16): e2303775, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38327094
4.
Stimulation of sigma receptors with afobazole blocks activation of microglia and reduces toxicity caused by amyloid-ß25-35.
J Pharmacol Exp Ther
; 347(2): 458-67, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24006337
5.
Afobazole activation of σ-1 receptors modulates neuronal responses to amyloid-ß25-35.
J Pharmacol Exp Ther
; 347(2): 468-77, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24006338
6.
In vitro evaluation of guanidine analogs as sigma receptor ligands for potential anti-stroke therapeutics.
J Pharmacol Exp Ther
; 344(1): 155-66, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23065135
7.
Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss.
bioRxiv
; 2023 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37090642
8.
Pathological Tau transmission initiated by binding lymphocyte-activation gene 3.
bioRxiv
; 2023 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37293032
9.
Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors.
J Pharmacol Exp Ther
; 339(1): 161-72, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21715561
10.
Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors.
J Pharmacol Exp Ther
; 339(1): 152-60, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21715562
11.
Activation of Sigma Receptors With Afobazole Modulates Microglial, but Not Neuronal, Apoptotic Gene Expression in Response to Long-Term Ischemia Exposure.
Front Neurosci
; 13: 414, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31156357
12.
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Front Aging Neurosci
; 11: 181, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31379560
13.
Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.
Sci Transl Med
; 9(420)2017 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29237760
14.
A modular approach to create a neurovascular unit-on-a-chip.
Lab Chip
; 13(4): 542-53, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23108480