Detalhe da pesquisa
1.
Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptors.
J Biol Chem
; 285(42): 32378-84, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20729214
2.
Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK.
J Cell Physiol
; 217(3): 652-66, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18651635
3.
Inhibition of the PI3K-Akt signaling pathway reduces tumor necrosis factor-alpha production in response to titanium particles in vitro.
J Bone Joint Surg Am
; 89(5): 1019-27, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17473139
4.
Titanium particles activate toll-like receptor 4 independently of lipid rafts in RAW264.7 murine macrophages.
J Orthop Res
; 29(2): 211-7, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20806319