Detalhe da pesquisa
1.
A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals a major role of BAX in the response to BH3 mimetics.
Blood
; 143(13): 1242-1258, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096363
2.
CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma.
Blood
; 142(18): 1543-1555, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562004
3.
Selective pharmacologic targeting of CTPS1 shows single-agent activity and synergizes with BCL2 inhibition in aggressive mantle cell lymphoma.
Haematologica
; 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38385294
4.
The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition.
Haematologica
; 107(12): 2905-2917, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263985
5.
Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma.
Blood
; 128(24): 2808-2818, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697772
6.
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion.
Exp Hematol Oncol
; 13(1): 34, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38528594
7.
BCLXL PROTAC degrader DT2216 targets secondary plasma cell leukemia addicted to BCLXL for survival.
Front Oncol
; 13: 1196005, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37534243
8.
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
Clin Epigenetics
; 13(1): 174, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34530900
9.
Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/BAK hetero-complexes.
Cell Death Dis
; 11(5): 316, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371863
10.
Stabilization of ß-catenin upon B-cell receptor signaling promotes NF-kB target genes transcription in mantle cell lymphoma.
Oncogene
; 39(14): 2934-2947, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034308
11.
Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells.
Cancers (Basel)
; 11(4)2019 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30925767
12.
CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages.
Leukemia
; 33(10): 2442-2453, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30940906
13.
BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker.
Front Oncol
; 8: 645, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30666297
14.
p53 regulates CD46 expression and measles virus infection in myeloma cells.
Blood Adv
; 2(23): 3492-3505, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530776