Detalhe da pesquisa
1.
Development of spiroguanidine-derived α7 neuronal nicotinic receptor partial agonists.
Bioorg Med Chem Lett
; 27(3): 578-581, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27993517
2.
Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.
Bioorg Med Chem Lett
; 27(5): 1261-1266, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28169167
3.
Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors.
J Pharmacol Exp Ther
; 356(2): 293-304, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582730
4.
Analysis of L-serine-O-phosphate in cerebrospinal spinal fluid by derivatization-liquid chromatography/mass spectrometry.
Anal Biochem
; 452: 10-2, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24534252
5.
Addressing the need for biomarker liquid chromatography/mass spectrometry assays: a protocol for effective method development for the bioanalysis of endogenous compounds in cerebrospinal fluid.
Rapid Commun Mass Spectrom
; 27(16): 1882-6, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23857934
6.
The Discovery of GSK3640254, a Next-Generation Inhibitor of HIV-1 Maturation.
J Med Chem
; 65(18): 11927-11948, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044257
7.
Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies.
Mol Ther Nucleic Acids
; 29: 625-642, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36090761
8.
Control of the stability of a protein-RNA complex by the position of fluorine in a base analogue.
J Am Chem Soc
; 133(11): 3687-9, 2011 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21361282
9.
Affinity and specificity of protein U1A-RNA complex formation based on an additive component free energy model.
J Mol Biol
; 371(5): 1405-19, 2007 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-17603075
10.
Recognition of essential purines by the U1A protein.
BMC Biochem
; 8: 22, 2007 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17980039
11.
Nicotinic alpha 7 receptor agonists EVP-6124 and BMS-933043, attenuate scopolamine-induced deficits in visuo-spatial paired associates learning.
PLoS One
; 12(12): e0187609, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29261656
12.
BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.
ACS Med Chem Lett
; 8(3): 366-371, 2017 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337332
13.
Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.
ACS Med Chem Lett
; 8(1): 133-137, 2017 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28105289
14.
Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents.
Eur J Pharmacol
; 807: 1-11, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438647
15.
40 Hz Auditory Steady-State Response Is a Pharmacodynamic Biomarker for Cortical NMDA Receptors.
Neuropsychopharmacology
; 41(9): 2232-40, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26837462
16.
The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia.
PLoS One
; 11(7): e0159996, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27467081
17.
Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.
J Med Chem
; 59(24): 11171-11181, 2016 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27958732
18.
Beyond classical derivatization: analyte 'derivatives' in the bioanalysis of endogenous and exogenous compounds.
Bioanalysis
; 7(19): 2501-13, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26466806
19.
Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry.
Bioanalysis
; 6(14): 1901-5, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25158962