Detalhe da pesquisa
1.
Structural and Functional Analysis of a ß2-Adrenergic Receptor Complex with GRK5.
Cell
; 169(3): 407-421.e16, 2017 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28431242
2.
Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting.
Mol Cell
; 81(2): 323-339.e11, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33321095
3.
G-protein-coupled receptors signal victory.
Cell
; 151(6): 1148-50, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23201142
4.
The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic ß-Cell Function and Diabetes.
Pharmacol Rev
; 76(2): 267-299, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38351071
5.
Identification of a ß-arrestin-biased negative allosteric modulator for the ß2-adrenergic receptor.
Proc Natl Acad Sci U S A
; 120(31): e2302668120, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490535
6.
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.
J Biol Chem
; 299(12): 105418, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923138
7.
Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4.
J Biol Chem
; 298(2): 101551, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34973340
8.
G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin.
J Biol Chem
; 298(10): 102421, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36030052
9.
Pepducin ICL1-9-Mediated ß2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner.
Cardiovasc Drugs Ther
; 37(2): 245-256, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34997361
10.
Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.
Trends Biochem Sci
; 43(7): 533-546, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735399
11.
PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells.
Am J Respir Cell Mol Biol
; 67(5): 550-561, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944139
12.
Phenylalanine 193 in Extracellular Loop 2 of the ß 2-Adrenergic Receptor Coordinates ß-Arrestin Interaction.
Mol Pharmacol
; 101(2): 87-94, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853152
13.
Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.
FASEB J
; 32(2): 862-874, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29042451
14.
G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel.
Mol Cell Biochem
; 461(1-2): 103-118, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363957
15.
ß-arrestin-biased signaling through the ß2-adrenergic receptor promotes cardiomyocyte contraction.
Proc Natl Acad Sci U S A
; 113(28): E4107-16, 2016 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27354517
16.
G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans.
J Biol Chem
; 292(14): 5943-5956, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213524
17.
Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
Mol Cell
; 40(6): 877-92, 2010 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21172654
18.
G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of ß-Arrestin.
Mol Pharmacol
; 91(6): 554-566, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28331048
19.
The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the ß2-Adrenergic Receptor.
J Biol Chem
; 291(28): 14510-25, 2016 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226565
20.
c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.
J Cell Biochem
; 118(1): 66-73, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27232975