1.
Mol Pharm
; 19(1): 354-357, 2022 01 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34889598
RESUMO
Two alkylated verdazyl radicals (AlkVZs) were investigated as active compounds for photoinitiated controlled MCF-7 cell death. Observed results unambiguously showed that AlkVZ could be a potential structural moiety for the design of a novel family of photodynamic therapy agents. The main advantage of the proposed substances is an oxygen-independent generation of active radicals, which play a pivotal role in the treatment of oxygen-deficient tumors.