Detalhe da pesquisa
1.
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition.
J Transl Med
; 22(1): 431, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38715059
2.
A first-in-human phase I trial of daily oral zelenirstat, a N-myristoyltransferase inhibitor, in patients with advanced solid tumors and relapsed/refractory B-cell lymphomas.
Invest New Drugs
; 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38837078
3.
N-myristoyltransferase proteins in breast cancer: prognostic relevance and validation as a new drug target.
Breast Cancer Res Treat
; 186(1): 79-87, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398478
4.
Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation.
J Biol Chem
; 291(49): 25678-25691, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27754867
5.
Membrane topology of human monoacylglycerol acyltransferase-2 and identification of regions important for its localization to the endoplasmic reticulum.
Biochim Biophys Acta
; 1861(9 Pt A): 1192-1204, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27373844
6.
Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin.
Hum Mol Genet
; 23(12): 3166-79, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24459296
7.
Palmitoylated TMX and calnexin target to the mitochondria-associated membrane.
EMBO J
; 31(2): 457-70, 2012 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22045338
8.
Characterization of the interaction of diacylglycerol acyltransferase-2 with the endoplasmic reticulum and lipid droplets.
Biochim Biophys Acta
; 1841(9): 1318-28, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24953780
9.
Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling.
J Cell Sci
; 126(Pt 17): 3893-903, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23843619
10.
N-Myristoyltransferase 1 interacts with calnexin at the endoplasmic reticulum.
Biochem Biophys Res Commun
; 468(4): 889-93, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603938
11.
Characterization of palmitoylation of ATP binding cassette transporter G1: effect on protein trafficking and function.
Biochim Biophys Acta
; 1831(6): 1067-78, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23388354
12.
Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases.
FASEB J
; 27(2): 811-21, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150525
13.
Tandem reporter assay for myristoylated proteins post-translationally (TRAMPP) identifies novel substrates for post-translational myristoylation: PKCε, a case study.
FASEB J
; 26(1): 13-28, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965604
14.
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.
Proc Natl Acad Sci U S A
; 106(30): 12365-70, 2009 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19617556
15.
Novel, First-in-Human, Oral PCLX-001 Treatment in a Patient with Relapsed Diffuse Large B-Cell Lymphoma.
Curr Oncol
; 29(3): 1939-1946, 2022 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323358
16.
Wnt acylation: seeing is believing.
Nat Chem Biol
; 10(1): 5-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24292072
17.
Palmitoylation of ketogenic enzyme HMGCS2 enhances its interaction with PPARalpha and transcription at the Hmgcs2 PPRE.
FASEB J
; 24(6): 1914-24, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124434
18.
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry.
J Lipid Res
; 51(6): 1566-80, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20028662
19.
The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore.
J Exp Med
; 196(9): 1127-39, 2002 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12417624
20.
Targeting N-myristoylation for therapy of B-cell lymphomas.
Nat Commun
; 11(1): 5348, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093447