Detalhe da pesquisa
1.
FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.
Blood
; 133(13): 1495-1506, 2019 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674471
2.
A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia.
Haematologica
; 106(12): 3090-3099, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34047175
3.
Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
Cancer
; 123(9): 1662-1673, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28055106
4.
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.
Blood
; 125(22): 3447-54, 2015 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25800051
5.
RXR is an essential component of the oncogenic PML/RARA complex in vivo.
Cancer Cell
; 12(1): 23-35, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17613434
6.
Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia.
Nat Med
; 13(6): 736-41, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17515895
7.
Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov
; 13(12): 2548-2565, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655965
8.
Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML).
Biomedicines
; 9(11)2021 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34829934
9.
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML.
Leukemia
; 35(9): 2552-2562, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33654209
10.
Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.
Cancer Discov
; 11(12): 3198-3213, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301789
11.
Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.
Nat Commun
; 9(1): 2047, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29795382
12.
Detection of Protein SUMOylation In Situ by Proximity Ligation Assays.
Methods Mol Biol
; 1475: 139-50, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27631803
13.
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.
J Cell Biol
; 204(6): 931-45, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637324
14.
PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.
Cancer Cell
; 18(1): 88-98, 2010 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20609355
15.
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.
Nat Med
; 14(12): 1333-42, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19029980