Detalhe da pesquisa
1.
A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Mol Ther
; 30(5): 1897-1912, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990810
2.
Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.
Proc Natl Acad Sci U S A
; 112(12): 3680-5, 2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775551
3.
Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin.
J Virol
; 90(1): 332-44, 2016 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26468547
4.
Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination.
J Immunol
; 195(4): 1617-27, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26170383
5.
Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants.
Proc Natl Acad Sci U S A
; 111(34): 12294-9, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25136133
6.
Positive Contribution of Adjuvanted Influenza Vaccines to the Resolution of Bacterial Superinfections.
J Infect Dis
; 213(12): 1876-85, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908732
7.
Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice.
Infect Immun
; 83(8): 3157-63, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26015481
8.
Evaluating the efficiency of isotope transmission for improved panel design and a comparison of the detection sensitivities of mass cytometer instruments.
Cytometry A
; 87(4): 357-68, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25704858
9.
Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells.
J Immunol
; 191(5): 2514-2525, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23904160
10.
The importance of adjuvant formulation in the development of a tuberculosis vaccine.
J Immunol
; 188(5): 2189-97, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22291184
11.
Evaluation of recombinant Leishmania polyprotein plus glucopyranosyl lipid A stable emulsion vaccines against sand fly-transmitted Leishmania major in C57BL/6 mice.
J Immunol
; 189(10): 4832-41, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045616
12.
Therapeutic immunization against Mycobacterium tuberculosis is an effective adjunct to antibiotic treatment.
J Infect Dis
; 207(8): 1242-52, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891286
13.
Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Vaccine
; 41(3): 724-734, 2023 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564274
14.
MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats.
Front Immunol
; 13: 1081156, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36713458
15.
2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness (Part 3 - Recommendations on Gene Therapy, Cell Therapy, Vaccine Assays; Immunogenicity of Biotherapeutics and Novel Modalities; Integrated Summary of Immunogenicity Harmonization).
Bioanalysis
; 14(11): 737-793, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35578991
16.
Evaluation of the safety and immunogenicity in rhesus monkeys of a recombinant malaria vaccine for Plasmodium vivax with a synthetic Toll-like receptor 4 agonist formulated in an emulsion.
Infect Immun
; 79(9): 3492-500, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21690242
17.
Single-Cell Analysis of Antigen-Specific CD8+ T-Cell Transcripts Reveals Profiles Specific to mRNA or Adjuvanted Protein Vaccines.
Front Immunol
; 12: 757151, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34777370
18.
2020 White Paper on Recent Issues in Bioanalysis: BAV Guidance, CLSI H62, Biotherapeutics Stability, Parallelism Testing, CyTOF and Regulatory Feedback (Part 2A - Recommendations on Biotherapeutics Stability, PK LBA Regulated Bioanalysis, Biomarkers Assays, Cytometry Validation & Innovation Part 2B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 13(5): 295-361, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33511867
19.
2020 White Paper on Recent Issues in Bioanalysis: Vaccine Assay Validation, qPCR Assay Validation, QC for CAR-T Flow Cytometry, NAb Assay Harmonization and ELISpot Validation (Part 3 - Recommendations on Immunogenicity Assay Strategies, NAb Assays, Biosimilars and FDA/EMA Immunogenicity Guidance/Guideline, Gene & Cell Therapy and Vaccine Assays).
Bioanalysis
; 13(6): 415-463, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33533276
20.
Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosis.
J Immunol
; 181(11): 7948-57, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19017986