Detalhe da pesquisa
1.
L'RRK de Triomphe: a solution for LRRK2 GTPase activity?
Biochem Soc Trans
; 44(6): 1625-1634, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913671
2.
A direct interaction between leucine-rich repeat kinase 2 and specific ß-tubulin isoforms regulates tubulin acetylation.
J Biol Chem
; 289(2): 895-908, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275654
3.
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.
Hum Mol Genet
; 21(22): 4966-79, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22899650
4.
The importance of Wnt signalling for neurodegeneration in Parkinson's disease.
Biochem Soc Trans
; 40(5): 1123-8, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988876
5.
The development of inhibitors of leucine-rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play.
Br J Pharmacol
; 179(8): 1478-1495, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050929
6.
A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction.
J Biol Chem
; 285(20): 15286-15295, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20228055
7.
LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same.
Mol Neurodegener
; 14(1): 49, 2019 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31864390
8.
Downregulated Wnt/ß-catenin signalling in the Down syndrome hippocampus.
Sci Rep
; 9(1): 7322, 2019 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086297
9.
Building Bridges In Neuropharmacology: New therapeutic approaches for psychiatric and neurodegenerative disorders.
Br J Pharmacol
; 179(8): 1475-1477, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35292961
10.
Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of ß-catenin signaling.
Mol Neurodegener
; 12(1): 9, 2017 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28103901
11.
Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.
Front Mol Neurosci
; 9: 18, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27013965
12.
Identifying protein kinase substrates: hunting for the organ-grinder's monkeys.
Trends Biochem Sci
; 29(5): 227-32, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15130558
13.
The regulation and deregulation of Wnt signaling by PARK genes in health and disease.
J Mol Cell Biol
; 6(1): 3-12, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24115276
14.
LRRK2: an éminence grise of Wnt-mediated neurogenesis?
Front Cell Neurosci
; 7: 82, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754980
15.
LRRK2 signaling pathways: the key to unlocking neurodegeneration?
Trends Cell Biol
; 21(5): 257-65, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21306901
16.
Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation.
Brain Res
; 1256: 8-18, 2009 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19135033
17.
The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes.
J Biol Chem
; 277(37): 33895-900, 2002 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12107176
18.
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.
J Cell Sci
; 117(Pt 25): 5985-93, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15546921