Detalhe da pesquisa
1.
Synthesis of erythro- B13 enantiomers and stereospecific action of full set of B13-isomers in MCF7 breast carcinoma cells: Cellular metabolism and effects on sphingolipids.
Bioorg Med Chem
; 32: 116011, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33461145
2.
Role of 1-Deoxysphingolipids in docetaxel neurotoxicity.
J Neurochem
; 154(6): 662-672, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32058598
3.
Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.
Proc Natl Acad Sci U S A
; 113(21): 5928-33, 2016 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27162368
4.
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Glia
; 66(3): 654-669, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193293
5.
Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes.
FASEB J
; 31(2): 771-780, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27836988
6.
Dose dependent actions of LCL521 on acid ceramidase and key sphingolipid metabolites.
Bioorg Med Chem
; 26(23-24): 6067-6075, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30448190
7.
Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration.
Proc Natl Acad Sci U S A
; 112(42): 12962-7, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438849
8.
Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.
J Lipid Res
; 58(7): 1439-1452, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28490444
9.
Sphingosine kinase 1 expression enhances colon tumor growth.
J Transl Med
; 15(1): 120, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28583134
10.
Cytokine-induced release of ceramide-enriched exosomes as a mediator of cell death signaling in an oligodendroglioma cell line.
J Lipid Res
; 57(11): 2028-2039, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27623848
11.
Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy.
J Biol Chem
; 290(4): 2053-68, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505239
12.
Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy.
FASEB J
; 29(11): 4461-72, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198449
13.
Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.
Biochim Biophys Acta
; 1841(11): 1571-80, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25195822
14.
Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy.
Ann Neurol
; 76(2): 206-12, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24782409
15.
Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer.
BMC Cancer
; 15: 762, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26493335
16.
Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide.
Int J Clin Oncol
; 20(3): 438-46, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25080062
17.
Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance.
Am J Physiol Endocrinol Metab
; 306(7): E756-68, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24473437
18.
Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.
BMC Cancer
; 14: 24, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24422988
19.
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
Nat Chem Biol
; 8(10): 831-8, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922758
20.
Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization.
Photochem Photobiol Sci
; 13(11): 1621-7, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25266739