Detalhe da pesquisa
1.
The aetiology and molecular landscape of insulin resistance.
Nat Rev Mol Cell Biol
; 22(11): 751-771, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285405
2.
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Cell
; 160(4): 745-758, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662011
3.
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Cell
; 151(3): 630-44, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23101630
4.
Regulated dynamic subcellular GLUT4 localization revealed by proximal proteome mapping in human muscle cells.
J Cell Sci
; 136(23)2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38126809
5.
Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
Nat Immunol
; 14(6): 611-8, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23644504
6.
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.
Cell
; 142(2): 270-83, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655468
7.
Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.
Immunity
; 41(1): 75-88, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25001241
8.
Tolerability, safety and pharmacodynamics of oral, small-molecule glucagon-like peptide-1 receptor agonist danuglipron for type 2 diabetes: A 12-week, randomized, placebo-controlled, Phase 2 study comparing different dose-escalation schemes.
Diabetes Obes Metab
; 25(10): 2805-2814, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311722
9.
Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development.
Immunity
; 49(2): 375-376, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30134202
10.
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Nature
; 494(7436): 256-60, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292513
11.
Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.
Proc Natl Acad Sci U S A
; 112(8): 2569-74, 2015 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25675494
12.
Insulin Is Required to Maintain Albumin Expression by Inhibiting Forkhead Box O1 Protein.
J Biol Chem
; 291(5): 2371-8, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668316
13.
Selective Activation of AMPK ß1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy.
J Pharmacol Exp Ther
; 361(2): 303-311, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28289077
14.
Akt-mediated foxo1 inhibition is required for liver regeneration.
Hepatology
; 63(5): 1660-74, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26473496
15.
Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.
J Immunol
; 195(5): 2452-60, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232429
16.
Glucagon: acute actions on hepatic metabolism.
Diabetologia
; 59(7): 1376-1381, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27115415
17.
The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivo.
Diabetologia
; 58(5): 1063-70, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25740694
18.
Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
J Biol Chem
; 288(47): 33966-33977, 2013 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24126911
19.
Akt recruits Dab2 to albumin endocytosis in the proximal tubule.
Am J Physiol Renal Physiol
; 307(12): F1380-9, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253241
20.
Construction of human activity-based phosphorylation networks.
Mol Syst Biol
; 9: 655, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23549483