Detalhe da pesquisa
1.
Impact of Direction of Transport on the Evaluation of Substrate Recognition of Mouse Multidrug and Toxin Extrusion Protein 1.
Drug Metab Dispos
; 51(5): 583-590, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669855
2.
Impact of Direction of Transport on the Evaluation of Inhibition Potencies of Multidrug and Toxin Extrusion Protein 1 Inhibitors.
Drug Metab Dispos
; 49(2): 152-158, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33262224
3.
Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines.
Biopharm Drug Dispos
; 40(1): 32-43, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30556139
4.
A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory Guidance.
Drug Metab Dispos
; 46(6): 865-878, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29487142
5.
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.
Clin Pharmacol Ther
; 113(4): 775-781, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35733280
6.
Physiologically-Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine.
CPT Pharmacometrics Syst Pharmacol
; 8(6): 396-406, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30821133
7.
Efficacy of the highly selective focal adhesion kinase inhibitor BI 853520 in adenocarcinoma xenograft models is linked to a mesenchymal tumor phenotype.
Oncogenesis
; 7(2): 21, 2018 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472531
8.
A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.
Chem Biol
; 12(4): 445-52, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15850981
9.
Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032.
J Antibiot (Tokyo)
; 57(4): 271-9, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15217192
10.
Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway.
Angew Chem Int Ed Engl
; 43(19): 2574-6, 2004 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15127456
11.
Fluorobalhimycin--a new chapter in glycopeptide antibiotic research.
Angew Chem Int Ed Engl
; 41(18): 3383-5, 2002 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12298039
12.
The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics-The Order of the Cyclization Steps This work was supported by the Deutsche Forschungsgemeinschaft (SFB 323) and by a grant of the EU (MEGATOP, QLK3-1999-00650). R. D. S. gratefully acknowledges the support of a Feodor-Lynen Fellowship granted by the Alexander-von-Humboldt Stiftung. We thank Corina Bihlmaier and Volker Pfeifer for help with transformation and Southern hybridization, J. A. Moss (La Jolla (USA)) for critical comments on the manuscript and Prof. Dr. M. E. Maier and Prof. Dr. H.-P. Fiedler (Tübingen) for generous support.
Angew Chem Int Ed Engl
; 40(24): 4688-4691, 2001 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12404385
13.
The detection of salmochelin and yersiniabactin in uropathogenic Escherichia coli strains by a novel hydrolysis-fluorescence-detection (HFD) method.
Int J Med Microbiol
; 295(2): 99-107, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15969470
14.
A mechanistic study of enantiomeric separation with vancomycin and balhimycin as chiral selectors by capillary electrophoresis. Dimerization and enantioselectivity.
Anal Chem
; 76(8): 2387-92, 2004 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15080752
15.
Evaluation of balhimycin as a chiral selector for enantioresolution by capillary electrophoresis.
Electrophoresis
; 25(16): 2687-92, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15351999
16.
Cyanopeptolin 963A, a chymotrypsin inhibitor of Microcystis PCC 7806.
J Nat Prod
; 67(10): 1755-7, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15497957
17.
Oscillapeptin J, a new grazer toxin of the freshwater cyanobacterium Planktothrix rubescens.
J Nat Prod
; 66(3): 431-4, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12662108
18.
Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine.
J Am Chem Soc
; 126(19): 5942-3, 2004 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15137740
19.
The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica.
Biometals
; 17(4): 471-81, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15259369
20.
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.
J Biol Chem
; 277(49): 47476-85, 2002 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12207020