Detalhe da pesquisa
1.
Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicity.
Toxicol Appl Pharmacol
; 487: 116956, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38735589
2.
Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.
Int J Toxicol
; 42(1): 19-36, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36523256
3.
A systematic approach to evaluate plausible modes of actions for mouse lung tumors in mice exposed to 4-methylimidozole.
Regul Toxicol Pharmacol
; 124: 104977, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34174380
4.
A toxicogenomic approach for the risk assessment of the food contaminant acetamide.
Toxicol Appl Pharmacol
; 388: 114872, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31881176
5.
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.
Regul Toxicol Pharmacol
; 96: 153-166, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29777725
6.
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.
Toxicol Appl Pharmacol
; 335: 28-40, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28951217
7.
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.
Toxicol Appl Pharmacol
; 332: 149-158, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28392392
8.
Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens.
Regul Toxicol Pharmacol
; 73(1): 339-47, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26210822
9.
Integrating gene expression and splicing dynamics across dose-response oxidative modulators.
Front Genet
; 15: 1389095, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38846964
10.
Mining toxicogenomic data for dose-responsive pathways: implications in advancing next-generation risk assessment.
Front Toxicol
; 5: 1272364, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38046401
11.
Biological system considerations for application of toxicogenomics in next-generation risk assessment and predictive toxicology.
Toxicol In Vitro
; 80: 105311, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35038564
12.
Testicular lumicrine factors regulate ERK, STAT, and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis.
Biol Reprod
; 84(6): 1282-91, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21311037
13.
RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days.
Data Brief
; 38: 107420, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34660856
14.
Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures.
Toxicol In Vitro
; 58: 1-12, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30807807
15.
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system.
Toxicol In Vitro
; 54: 41-57, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30218698
16.
A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation.
Front Pharmacol
; 9: 1072, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333746
17.
Editor's Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis.
Toxicol Sci
; 155(1): 85-100, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27664422
18.
MYC is an early response regulator of human adipogenesis in adipose stem cells.
PLoS One
; 9(12): e114133, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25437437
19.
Comparison of microarrays and RNA-seq for gene expression analyses of dose-response experiments.
Toxicol Sci
; 137(2): 385-403, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194394
20.
IVT-seq reveals extreme bias in RNA sequencing.
Genome Biol
; 15(6): R86, 2014 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24981968