Detalhe da pesquisa
1.
ARGX-117, a therapeutic complement inhibiting antibody targeting C2.
J Allergy Clin Immunol
; 147(4): 1420-1429.e7, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32926878
2.
A bispecific antibody strategy to target multiple type 2 cytokines in asthma.
J Allergy Clin Immunol
; 142(4): 1185-1193.e4, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29890236
3.
Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.
J Biol Chem
; 291(26): 13846-54, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27129274
4.
Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function.
J Biol Chem
; 288(35): 25173-25182, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23836909
5.
Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.
Retrovirology
; 11: 83, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25700025
6.
Increased expression of IL-24 in chronic spontaneous urticaria.
Allergy
; 74(9): 1811-1813, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006117
7.
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells.
Proc Natl Acad Sci U S A
; 107(47): 20565-70, 2010 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21059953
8.
Development and characterization of agonistic antibodies targeting the Ig-like 1 domain of MuSK.
Sci Rep
; 13(1): 7478, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156800
9.
Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy.
Neurol Neuroimmunol Neuroinflamm
; 9(1)2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34759020
10.
A Targetable, Noncanonical Signal Transducer and Activator of Transcription 3 Activation Induced by the Y-Less Region of IL-22 Receptor Orchestrates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice.
J Invest Dermatol
; 141(11): 2668-2678.e6, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33992648
11.
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy.
Mol Ther Methods Clin Dev
; 21: 369-381, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33898634
12.
Caspase-3 regulates catalytic activity and scaffolding functions of the protein tyrosine phosphatase PEST, a novel modulator of the apoptotic response.
Mol Cell Biol
; 27(3): 1172-90, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17130234
13.
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science
; 364(6442)2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31123109
14.
The ROS-NOX connection in cancer and angiogenesis.
Crit Rev Eukaryot Gene Expr
; 18(1): 35-45, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18197784
15.
Therapeutic bispecific antibody formats: a patent applications review (1994-2017).
Expert Opin Ther Pat
; 28(3): 251-276, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366356
16.
Personalized medicine with biologics for severe type 2 asthma: current status and future prospects.
MAbs
; 10(1): 34-45, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29035619
17.
DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops.
MAbs
; 8(6): 1126-35, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27211075
18.
Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics.
Protein Eng Des Sel
; 29(4): 123-33, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26945588
19.
Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy.
Sci Rep
; 6: 31621, 2016 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27546726
20.
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs
; 7(4): 693-706, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26018625