Detalhe da pesquisa
1.
Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial.
Lancet Oncol
; 23(1): 53-64, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838156
2.
Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial.
Lancet Oncol
; 21(9): 1234-1243, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818466
3.
Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial.
Nat Med
; 29(5): 1103-1112, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059834
4.
The regulatory role of the juxtamembrane region in the activity of the epidermal growth factor receptor.
Biochem Soc Trans
; 40(1): 195-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22260689
5.
Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
PLoS Comput Biol
; 7(12): e1002319, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22219718
6.
Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses.
Mol Oncol
; 13(8): 1725-1743, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31116490
7.
Neuroprotective effects of 3,6'-disinapoyl sucrose through increased BDNF levels and CREB phosphorylation via the CaMKII and ERK1/2 pathway.
J Mol Neurosci
; 53(4): 600-7, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24488601
8.
A potential peptide therapeutic derived from the juxtamembrane domain of the epidermal growth factor receptor.
PLoS One
; 7(11): e49702, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23166750
9.
Identification of new Gßγ interaction sites in adenylyl cyclase 2.
Cell Signal
; 23(9): 1489-95, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596131
10.
Systems pharmacology.
Mt Sinai J Med
; 77(4): 333-44, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20687178
11.
Systems approaches to polypharmacology and drug discovery.
Curr Opin Drug Discov Devel
; 13(3): 297-309, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20443163