Detalhe da pesquisa
1.
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.
J Biol Chem
; 299(6): 104749, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100284
2.
Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Proc Natl Acad Sci U S A
; 118(21)2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006641
3.
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.
Mol Ther
; 30(5): 1885-1896, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34687845
4.
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Mol Ther
; 30(9): 2998-3016, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526097
5.
Extracellular Vesicles and Viruses: Two Intertwined Entities.
Int J Mol Sci
; 24(2)2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674550
6.
CHESPA/CHESCA-SPARKY: automated NMR data analysis plugins for SPARKY to map protein allostery.
Bioinformatics
; 37(8): 1176-1177, 2021 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32926121
7.
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.
Mol Ther
; 29(6): 1984-2000, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33578036
8.
Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.
Int J Mol Sci
; 22(5)2021 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33668756
9.
Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding.
Biophys J
; 119(6): 1135-1146, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32882185
10.
Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia.
J Biol Chem
; 292(15): 6414-6428, 2017 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174302
11.
Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist.
J Am Chem Soc
; 140(30): 9624-9637, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30016089
12.
Direct binding and internalization of diverse extracellular nucleic acid species through the collagenous domain of class A scavenger receptors.
Immunol Cell Biol
; 96(9): 922-934, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617041
13.
Advances in NMR Methods To Map Allosteric Sites: From Models to Translation.
Chem Rev
; 116(11): 6267-304, 2016 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27111288
14.
A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
J Biol Chem
; 289(32): 22205-20, 2014 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24878962
15.
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR.
Biochem Soc Trans
; 42(2): 302-7, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24646235
16.
Allosteric linkers in cAMP signalling.
Biochem Soc Trans
; 42(1): 139-44, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24450641
17.
A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.
Mol Ther Methods Clin Dev
; 31: 101110, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37822719
18.
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.
Nat Commun
; 14(1): 3035, 2023 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236967
19.
Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.
Front Immunol
; 13: 1029269, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36405739
20.
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.
Front Immunol
; 13: 1050250, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36713447