Detalhe da pesquisa
1.
In vitro activity of rifabutin against 293 contemporary carbapenem-resistant Acinetobacter baumannii clinical isolates and characterization of rifabutin mode of action and resistance mechanisms.
J Antimicrob Chemother
; 75(12): 3552-3562, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32869081
2.
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Bioorg Med Chem
; 26(4): 945-956, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28818461
3.
Identification of novel TACE inhibitors compatible with topical application.
Bioorg Med Chem Lett
; 27(8): 1848-1853, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274635
4.
Design and synthesis of water-soluble prodrugs of rifabutin for intraveneous administration.
Eur J Med Chem
; 238: 114515, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35691174
5.
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Virulence
; 13(1): 1868-1883, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261919
6.
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Sci Transl Med
; 14(643): eaaz6280, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507672
7.
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem
; 167: 426-438, 2019 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784877
8.
Efficient analoging around ethionamide to explore thioamides bioactivation pathways triggered by boosters in Mycobacterium tuberculosis.
Eur J Med Chem
; 159: 35-46, 2018 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30268015
9.
Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox.
J Med Chem
; 60(21): 9067-9089, 2017 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985084
10.
Identification of New Nonsteroidal RORα Ligands; Related Structure-Activity Relationships and Docking Studies.
ACS Med Chem Lett
; 4(6): 504-8, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900700