Detalhe da pesquisa
1.
Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response.
Mol Ther
; 24(10): 1873-1880, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27456061
2.
Chim3 confers survival advantage to CD4+ T cells upon HIV-1 infection by preventing HIV-1 DNA integration and HIV-1-induced G2 cell-cycle delay.
Blood
; 115(20): 4021-9, 2010 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20220118
3.
The F12-Vif derivative Chim3 inhibits HIV-1 replication in CD4+ T lymphocytes and CD34+-derived macrophages by blocking HIV-1 DNA integration.
Blood
; 113(15): 3443-52, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19211937
4.
Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase.
Nucleic Acids Res
; 42(6): 4144, 2014 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24627181
5.
Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase.
Nucleic Acids Res
; 37(11): 3660-9, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19369217
6.
Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.
Mol Ther
; 17(5): 851-6, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19293778
7.
Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein.
Mol Ther Methods Clin Dev
; 4: 102-114, 2017 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28344996
8.
Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes.
Mol Ther Methods Clin Dev
; 5: 22-30, 2017 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28480301
9.
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.
Sci Transl Med
; 9(411)2017 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29021165
10.
Production of lentiviral vectors.
Mol Ther Methods Clin Dev
; 3: 16017, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27110581
11.
RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope.
Mol Ther Methods Clin Dev
; 3: 16033, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27222840
12.
IFN-gamma and IL-12 differentially regulate CC-chemokine secretion and CCR5 expression in human T lymphocytes.
J Leukoc Biol
; 72(4): 735-42, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12377943
13.
Blocking HIV-1 Vif restores a natural mechanism of intracellular antiviral defense.
Curr Drug Targets Immune Endocr Metabol Disord
; 4(4): 257-63, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15578976
14.
Therapeutic genes for anti-HIV/AIDS gene therapy.
Curr Pharm Biotechnol
; 14(5): 488-500, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-22429132
15.
RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy.
Hum Gene Ther Methods
; 24(4): 228-40, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23767932
16.
Naturally occurring C-terminally truncated STAT5 is a negative regulator of HIV-1 expression.
Blood
; 109(12): 5380-9, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332243
17.
Heterogeneity of signal transducer and activator of transcription binding sites in the long-terminal repeats of distinct HIV-1 subtypes.
Open Virol J
; 1: 26-32, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-19440456
18.
T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner.
Mol Ther
; 12(4): 697-706, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16039909
19.
Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor.
Blood
; 99(1): 224-31, 2002 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11756175
20.
Retroviral interference on STAT activation in individuals coinfected with human T cell leukemia virus type 2 and HIV-1.
J Immunol
; 169(8): 4443-9, 2002 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370379