Detalhe da pesquisa
1.
Safety and Efficacy of Dexpramipexole in Eosinophilic Asthma (EXHALE): A randomized controlled trial.
J Allergy Clin Immunol
; 152(5): 1121-1130.e10, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277072
2.
Dexpramipexole as an oral steroid-sparing agent in hypereosinophilic syndromes.
Blood
; 132(5): 501-509, 2018 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29739754
3.
The targeted eosinophil-lowering effects of dexpramipexole in clinical studies.
Blood Cells Mol Dis
; 63: 62-65, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178599
4.
Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.
Laryngoscope
; 129(2): E61-E66, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30284267
5.
Association Between Decline in Slow Vital Capacity and Respiratory Insufficiency, Use of Assisted Ventilation, Tracheostomy, or Death in Patients With Amyotrophic Lateral Sclerosis.
JAMA Neurol
; 75(1): 58-64, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29181534
6.
A post hoc analysis of subgroup outcomes and creatinine in the phase III clinical trial (EMPOWER) of dexpramipexole in ALS.
Amyotroph Lateral Scler Frontotemporal Degener
; 15(5-6): 406-13, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25125035
7.
Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial.
Lancet Neurol
; 12(11): 1059-67, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24067398
8.
Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects.
J Clin Pharmacol
; 51(8): 1177-85, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959524
9.
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis.
Nat Med
; 17(12): 1652-6, 2011 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22101764
10.
KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis.
CNS Neurosci Ther
; 14(3): 215-26, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18801114