Detalhe da pesquisa
1.
Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
EMBO J
; 41(13): e109755, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35593068
2.
Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A.
Angew Chem Int Ed Engl
; 63(3): e202314028, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38029352
3.
The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain.
Chembiochem
; 24(5): e202200455, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538283
4.
High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin.
J Nat Prod
; 85(3): 530-539, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263115
5.
Human commensals producing a novel antibiotic impair pathogen colonization.
Nature
; 535(7613): 511-6, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466123
6.
Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii.
Mar Drugs
; 20(8)2022 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005535
7.
Synthesis of tryptophan-dehydrobutyrine diketopiperazine and biological activity of hangtaimycin and its co-metabolites.
Beilstein J Org Chem
; 18: 1159-1165, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36128431
8.
The Antibiotic Negamycin Crosses the Bacterial Cytoplasmic Membrane by Multiple Routes.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468467
9.
Generation of Lasso Peptide-Based ClpP Binders.
Int J Mol Sci
; 23(1)2021 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008890
10.
Nocathioamides, Uncovered by a Tunable Metabologenomic Approach, Define a Novel Class of Chimeric Lanthipeptides.
Angew Chem Int Ed Engl
; 60(30): 16472-16479, 2021 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33991039
11.
Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33046497
12.
Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Proteaseâ P Independent of Its Oligomeric and Activity State.
Chembiochem
; 21(1-2): 235-240, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31487112
13.
New Nocobactin Derivatives with Antimuscarinic Activity, Terpenibactins A-C, Revealed by Genome Mining of Nocardia terpenica IFM 0406.
Chembiochem
; 21(15): 2205-2213, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196864
14.
Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes.
Chembiochem
; 21(14): 1997-2012, 2020 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181548
15.
Nostotrebin 6 Related Cyclopentenediones and δ-Lactones with Broad Activity Spectrum Isolated from the Cultivation Medium of the Cyanobacterium Nostoc sp. CBT1153.
J Nat Prod
; 83(2): 392-400, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31977209
16.
Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action.
PLoS Pathog
; 13(3): e1006261, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28323883
17.
Consequences of dosing and timing on the antibacterial effects of ADEP antibiotics.
Int J Med Microbiol
; 309(7): 151329, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331697
18.
Environmental and cellular factors affecting the localization of T6SS proteins in Burkholderia thailandensis.
Int J Med Microbiol
; 309(6): 151335, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31378704
19.
The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor.
Appl Environ Microbiol
; 85(20)2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31399403
20.
Synthetic Lugdunin Analogues Reveal Essential Structural Motifs for Antimicrobial Action and Proton Translocation Capability.
Angew Chem Int Ed Engl
; 58(27): 9234-9238, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31059155