Detalhe da pesquisa
1.
The FAM13A Long Isoform Regulates Cilia Movement and Co-ordination in Airway Mucociliary Transport.
Am J Respir Cell Mol Biol
; 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38691660
2.
GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice.
J Biol Chem
; 297(2): 100928, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274316
3.
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature
; 488(7411): 404-8, 2012 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22842901
4.
Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity.
Bioorg Med Chem
; 23(21): 7000-6, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455654
5.
Kruidenier et al. reply.
Nature
; 514(7520): E2, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25279927
6.
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data.
J Biol Chem
; 288(30): 22080-95, 2013 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709268
7.
5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors.
Bioorg Med Chem Lett
; 22(5): 1989-94, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22310227
8.
Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET.
Cell Chem Biol
; 29(1): 19-29.e6, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038748
9.
Discovery of functionally distinct anti-C7 monoclonal antibodies and stratification of anti-nicotinic AChR positive Myasthenia Gravis patients.
Front Immunol
; 13: 968206, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36148231
10.
Identification of 2-(4-pyridyl)thienopyridinones as GSK-3ß inhibitors.
Bioorg Med Chem Lett
; 21(16): 4823-7, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21764580
11.
MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions.
Pharmacol Res Perspect
; 7(6): e00547, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31832205
12.
A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.
J Med Chem
; 62(16): 7506-7525, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31398032
13.
Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures.
Neurosci Lett
; 673: 44-50, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29499308
14.
Decorating Self-Assembled Peptide Cages with Proteins.
ACS Nano
; 11(8): 7901-7914, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28686416
15.
The structure of MSK1 reveals a novel autoinhibitory conformation for a dual kinase protein.
Structure
; 12(6): 1067-77, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15274926
16.
Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.
J Med Chem
; 58(14): 5649-73, 2015 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26155854
17.
Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.
Antioxid Redox Signal
; 23(5): 358-74, 2015 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26135714
18.
CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.
J Med Chem
; 46(19): 4070-86, 2003 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-12954060
19.
Potential of real-time measurement of GFP-fusion proteins.
J Biotechnol
; 109(1-2): 201-11, 2004 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15063628
20.
Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a model system.
J Biomol Screen
; 19(2): 278-86, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23896685