Detalhe da pesquisa
1.
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.
Biol Chem
; 403(5-6): 495-508, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35073465
2.
A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder.
Genet Med
; 24(7): 1567-1582, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482014
3.
Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids.
Nucleic Acids Res
; 47(10): e55, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30809660
4.
Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression.
Nucleic Acids Res
; 47(2): 953-969, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462278
5.
Engineering therapeutic bispecific antibodies using CrossMab technology.
Methods
; 154: 21-31, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30453028
6.
Engineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery.
Immunol Rev
; 270(1): 165-77, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864111
7.
Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing.
Biol Chem
; 400(3): 343-350, 2019 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763031
8.
Interplay between reversible phosphorylation and irreversible ADP-ribosylation of eukaryotic translation elongation factor 2.
Biol Chem
; 400(4): 501-512, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30218597
9.
Transcytosis of payloads that are non-covalently complexed to bispecific antibodies across the hCMEC/D3 blood-brain barrier model.
Biol Chem
; 399(7): 711-721, 2018 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29466231
10.
Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.
Proc Natl Acad Sci U S A
; 112(34): 10732-7, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261303
11.
A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder.
Genet Med
; 24(10): 2207, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36205747
12.
Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.
FASEB J
; 29(5): 1763-79, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670234
13.
A novel glycoengineered bispecific antibody format for targeted inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor type I (IGF-1R) demonstrating unique molecular properties.
J Biol Chem
; 289(27): 18693-706, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841203
14.
TriFabs--Trivalent IgG-Shaped Bispecific Antibody Derivatives: Design, Generation, Characterization and Application for Targeted Payload Delivery.
Int J Mol Sci
; 16(11): 27497-507, 2015 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26593903
15.
Bispecific digoxigenin-binding antibodies for targeted payload delivery.
Proc Natl Acad Sci U S A
; 108(20): 8194-9, 2011 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536919
16.
Diphthamide - a conserved modification of eEF2 with clinical relevance.
Trends Mol Med
; 30(2): 164-177, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38097404
17.
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control.
Bioanalysis
; 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38497775
18.
Functional Integrity of Radical SAM Enzyme Dph1â¢Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines.
Biomolecules
; 14(4)2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672486
19.
The present and future of bispecific antibodies for cancer therapy.
Nat Rev Drug Discov
; 23(4): 301-319, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38448606
20.
Human-protein-derived peptides for intracellular delivery of biomolecules.
Biochem J
; 442(3): 583-93, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22150630