Detalhe da pesquisa
1.
Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Respir Med
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38705167
2.
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity.
Cancer Cell
; 41(6): 1073-1090.e12, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236195
3.
Results of a Phase 2b Trial With GB001, a Prostaglandin D2 Receptor 2 Antagonist, in Moderate to Severe Eosinophilic Asthma.
Chest
; 162(2): 297-308, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35248549
4.
Randomised clinical trial: a phase 1b study of GB004, an oral HIF-1α stabiliser, for treatment of ulcerative colitis.
Aliment Pharmacol Ther
; 55(4): 401-411, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014040
5.
TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension.
Pulm Circ
; 11(4): 20458940211057071, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34790348
6.
The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways.
J Exp Med
; 196(12): 1605-15, 2002 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486103
7.
Mice lacking bi-1 gene show accelerated liver regeneration.
Cancer Res
; 67(4): 1442-50, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17308082
8.
Development of a PD-L1 Complementary Diagnostic Immunohistochemistry Assay (SP142) for Atezolizumab.
Appl Immunohistochem Mol Morphol
; 27(2): 92-100, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29346180
9.
Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death.
Biochim Biophys Acta
; 1762(8): 742-54, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16920334
10.
Effect of Fluorouracil, Leucovorin, and Oxaliplatin With or Without Onartuzumab in HER2-Negative, MET-Positive Gastroesophageal Adenocarcinoma: The METGastric Randomized Clinical Trial.
JAMA Oncol
; 3(5): 620-627, 2017 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27918764
11.
Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA Methyltransferase Biomarker Analyses.
J Clin Oncol
; 35(3): 343-351, 2017 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27918718
12.
Editorial: protecting hypoxia-inducible factor 1a and gut integrity with GB004-a promising therapeutic approach for ulcerative colitis? Authors' reply.
Aliment Pharmacol Ther
; 55(6): 735-736, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245951
13.
Dysregulation of receptor interacting protein-2 and caspase recruitment domain only protein mediates aberrant caspase-1 activation in Huntington's disease.
J Neurosci
; 25(50): 11645-54, 2005 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16354923
14.
HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development.
Oncotarget
; 5(10): 2866-80, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24930887
15.
Exon scanning by reverse transcriptase-polymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer.
Cancer Genet
; 204(1): 45-52, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21356191
16.
Plasma tyrosine kinase activity as a potential biomarker in BCR-ABL1-targeted therapy.
Cancer Biomark
; 7(6): 295-303, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21694468
17.
Circulating Ki-67 protein in plasma as a biomarker and prognostic indicator of acute lymphoblastic leukemia.
Leuk Res
; 34(2): 173-6, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679351
18.
JAK2 exon 14 deletion in patients with chronic myeloproliferative neoplasms.
PLoS One
; 5(8): e12165, 2010 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20730051
19.
Circulating Ki-67 index in plasma as a biomarker and prognostic indicator in chronic lymphocytic leukemia.
Leuk Res
; 34(10): 1320-4, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20362333
20.
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.
Proc Natl Acad Sci U S A
; 104(15): 6371-6, 2007 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17404240