Detalhe da pesquisa
1.
Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics.
FASEB J
; 36(3): e22208, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192204
2.
Serum albumin-binding VH Hs with variable pH sensitivities enable tailored half-life extension of biologics.
FASEB J
; 34(6): 8155-8171, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342547
3.
Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.
J Physiol
; 596(3): 445-475, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023798
4.
Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity.
J Neurochem
; 146(6): 735-752, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29877588
5.
Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.
Mol Pharm
; 15(4): 1420-1431, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29485883
6.
Brain penetration, target engagement, and disposition of the blood-brain barrier-crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1.
FASEB J
; 30(5): 1927-40, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26839377
7.
A novel platform for engineering blood-brain barrier-crossing bispecific biologics.
FASEB J
; 28(11): 4764-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070367
8.
Multiplexed evaluation of serum and CSF pharmacokinetics of brain-targeting single-domain antibodies using a NanoLC-SRM-ILIS method.
Mol Pharm
; 10(5): 1542-56, 2013 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150993
9.
Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction.
J Biochem
; 173(2): 95-105, 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346120
10.
Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat.
Pharmaceutics
; 15(5)2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242805
11.
Preconditioning induces tolerance by suppressing glutamate release in neuron culture ischemia models.
J Neurochem
; 122(2): 470-81, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607164
12.
Neuroprotection against supra-lethal 'stroke in a dish' insults by an anti-excitotoxic receptor antagonist cocktail.
Neurochem Int
; 158: 105381, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764225
13.
Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor.
Pharmaceutics
; 14(7)2022 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890347
14.
Defining the epitope of a blood-brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor.
Sci Rep
; 11(1): 4284, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33608571
15.
Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human.
Fluids Barriers CNS
; 17(1): 47, 2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698806
16.
Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier.
J Cereb Blood Flow Metab
; 38(4): 727-740, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29140158
17.
An alternative Ca2+-dependent mechanism of neuroprotection by the metalloporphyrin class of superoxide dismutase mimetics.
FASEB J
; 19(12): 1734-6, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16081500
18.
Competing approaches to excitotoxic neuroprotection by inert and catalytic antioxidant porphyrins.
Neurosci Lett
; 401(3): 236-41, 2006 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16631306
19.
Failure and rescue of preconditioning-induced neuroprotection in severe stroke-like insults.
Neuropharmacology
; 105: 533-542, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26867506
20.
The dual role of prostaglandin E(2) in excitotoxicity and preconditioning-induced neuroprotection.
Eur J Pharmacol
; 517(1-2): 17-27, 2005 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15964567