Detalhe da pesquisa
1.
Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis.
Pharmaceutics
; 14(7)2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890315
2.
Comprehensive in Vitro Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology.
ACS Pharmacol Transl Sci
; 4(6): 1818-1834, 2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34927013
3.
First-in-Human Randomized Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the KDM1A Inhibitor Vafidemstat.
CNS Drugs
; 35(3): 331-344, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755924
4.
First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia.
J Clin Oncol
; 38(36): 4260-4273, 2020 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33052756
5.
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Cancer Cell
; 33(3): 495-511.e12, 2018 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29502954
6.
Advances in the development of histone lysine demethylase inhibitors.
Curr Opin Pharmacol
; 23: 52-60, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26057211
7.
KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.
Epigenomics
; 7(4): 609-26, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111032
8.
DNA chip technology in brain banks: confronting a degrading world.
J Neuropathol Exp Neurol
; 63(10): 1003-14, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15535128
9.
Reduced ubiquitin C-terminal hydrolase-1 expression levels in dementia with Lewy bodies.
Neurobiol Dis
; 22(2): 265-73, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16380264
10.
Mouse neuron navigator 1, a novel microtubule-associated protein involved in neuronal migration.
Mol Cell Neurosci
; 28(4): 599-612, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15797708
11.
Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.
Genomics
; 80(1): 21-30, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12079279
12.
Chromatin organization during spermiogenesis in Octopus vulgaris. II: DNA-interacting proteins.
Mol Reprod Dev
; 68(2): 232-9, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15095345