Detalhe da pesquisa
1.
Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Mol Pharm
; 20(7): 3367-3379, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37260417
2.
Systematic evaluation of structure-property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride.
Bioorg Med Chem
; 37: 116116, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33799173
3.
Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors.
Int J Mol Sci
; 22(6)2021 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804289
4.
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Cell Chem Biol
; 31(4): 683-698.e7, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38151019
5.
Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs.
Front Cell Infect Microbiol
; 13: 1101568, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923593
6.
6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist.
Biomolecules
; 12(9)2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139148
7.
An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.
Commun Biol
; 5(1): 166, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210534