Detalhe da pesquisa
1.
NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain.
Proc Natl Acad Sci U S A
; 117(33): 20292-20297, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747529
2.
Systems-level identification of PKA-dependent signaling in epithelial cells.
Proc Natl Acad Sci U S A
; 114(42): E8875-E8884, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973931
3.
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.
Proc Natl Acad Sci U S A
; 114(46): E9989-E9998, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089413
4.
Cross-Sectional Positive Association of Serum Lipids and Blood Pressure With Serum Sodium Within the Normal Reference Range of 135-145 mmol/L.
Arterioscler Thromb Vasc Biol
; 37(3): 598-606, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062505
5.
Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis.
Proc Natl Acad Sci U S A
; 111(17): 6485-90, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24733925
6.
Peptide affinity analysis of proteins that bind to an unstructured NH2-terminal region of the osmoprotective transcription factor NFAT5.
Physiol Genomics
; 48(4): 290-305, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757802
7.
Peptide affinity analysis of proteins that bind to an unstructured region containing the transactivating domain of the osmoprotective transcription factor NFAT5.
Physiol Genomics
; 48(11): 835-849, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27764768
8.
High NaCl- and urea-induced posttranslational modifications that increase glycerophosphocholine by inhibiting GDPD5 phosphodiesterase.
Proc Natl Acad Sci U S A
; 110(18): 7482-7, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589856
9.
Reply to Edemir: Physiological regulation and single-cell RNA sequencing.
Proc Natl Acad Sci U S A
; 115(3): E351-E352, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311339
10.
RNA-Seq analysis of high NaCl-induced gene expression.
Physiol Genomics
; 47(10): 500-13, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220925
11.
PKC-α contributes to high NaCl-induced activation of NFAT5 (TonEBP/OREBP) through MAPK ERK1/2.
Am J Physiol Renal Physiol
; 308(2): F140-8, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391900
12.
Expression, fermentation and purification of a predicted intrinsically disordered region of the transcription factor, NFAT5.
Protein Expr Purif
; 115: 141-5, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26256058
13.
Global discovery of high-NaCl-induced changes of protein phosphorylation.
Am J Physiol Cell Physiol
; 307(5): C442-54, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24965592
14.
Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C-gamma1 to activation of the osmoprotective transcription factor NFAT5.
Proc Natl Acad Sci U S A
; 108(29): 12155-60, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21712438
15.
DNA double-strand breaks induced by high NaCl occur predominantly in gene deserts.
Proc Natl Acad Sci U S A
; 108(51): 20796-801, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22106305
16.
Inhibitory phosphorylation of GSK-3ß by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP).
Am J Physiol Renal Physiol
; 304(7): F908-17, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23324178
17.
High NaCl-induced inhibition of PTG contributes to activation of NFAT5 through attenuation of the negative effect of SHP-1.
Am J Physiol Renal Physiol
; 305(3): F362-9, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23720348
18.
Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP.
Proc Natl Acad Sci U S A
; 107(15): 7072-7, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351292
19.
Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP.
Proc Natl Acad Sci U S A
; 107(2): 906-11, 2010 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080774
20.
Mutations that reduce its specific DNA binding inhibit high NaCl-induced nuclear localization of the osmoprotective transcription factor NFAT5.
Am J Physiol Cell Physiol
; 303(10): C1061-9, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22992674