Detalhe da pesquisa
1.
Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Nat Immunol
; 25(2): 371-372, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38087084
2.
CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Nat Immunol
; 17(7): 816-24, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27213690
3.
HBO1 is required for the maintenance of leukaemia stem cells.
Nature
; 577(7789): 266-270, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827282
4.
Microbiological Characterization of VNRX-5236, a Broad-Spectrum ß-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agent against Strains of Enterobacterales Expressing Extended-Spectrum ß-Lactamases and Serine Carbapenemases.
Antimicrob Agents Chemother
; 65(8): e0055221, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001510
5.
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-ß-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871094
6.
Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.
Blood
; 129(13): 1823-1830, 2017 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188131
7.
Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9.
Bioorg Med Chem
; 23(19): 6280-96, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26349627
8.
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden.
BMC Cancer
; 14: 317, 2014 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24886434
9.
A novel, reverse-phase-shifting, thermoreversible foaming hydrogel containing antibiotics for the treatment of thermal burns in a swine model - A pilot study.
Burns
; 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582695
10.
Chromatin targeting: A BET inhibitor workaround.
Nat Chem Biol
; 12(7): 469-70, 2016 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27315535
11.
CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms.
Blood
; 115(25): 5232-40, 2010 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385788
12.
Synthesis and biological evaluation of a potent salicylihalamide A lactam analogue.
Org Biomol Chem
; 10(40): 8147-53, 2012 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22964776
13.
The microtubule depolymerizing agent CYT997 causes extensive ablation of tumor vasculature in vivo.
J Pharmacol Exp Ther
; 339(3): 799-806, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21917561
14.
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 21(11): 3227-31, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550237
15.
Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable ß-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes.
J Med Chem
; 64(14): 10155-10166, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34191513
16.
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 20(9): 2968-73, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20347591
17.
Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages.
J Leukoc Biol
; 85(2): 278-88, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19004987
18.
A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun
; 11(1): 3024, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541684
19.
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-ß-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
J Med Chem
; 63(6): 2789-2801, 2020 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31765155
20.
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Cell Rep
; 31(1): 107492, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32268090