Detalhe da pesquisa
1.
Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma.
Br J Cancer
; 125(10): 1365-1376, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34588615
2.
Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ß-propeller domain.
Proc Natl Acad Sci U S A
; 111(14): 5195-200, 2014 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24706829
3.
BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.
J Pathol
; 227(2): 200-8, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22190288
4.
BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms.
Oncogene
; 42(8): 572-585, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36550359
5.
Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial.
EClinicalMedicine
; 48: 101432, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35706488
6.
Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.
Sci Rep
; 11(1): 7434, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33795785
7.
BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma.
Mol Cancer Ther
; 20(2): 379-388, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33158996
8.
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment.
Nat Commun
; 12(1): 1751, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33741915
9.
MicroRNA signature of malignant mesothelioma with potential diagnostic and prognostic implications.
Am J Respir Cell Mol Biol
; 42(3): 312-9, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19502386
10.
Ganetespib in Combination with Pemetrexed-Platinum Chemotherapy in Patients with Pleural Mesothelioma (MESO-02): A Phase Ib Trial.
Clin Cancer Res
; 26(18): 4748-4755, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669375
11.
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.
Elife
; 72018 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29345617
12.
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents.
J Med Chem
; 49(17): 5372-6, 2006 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16913727
13.
Author Correction: Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment.
Nat Commun
; 12(1): 3569, 2021 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099722
14.
BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma.
PLoS One
; 8(6): e65489, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23762382
15.
Phase II clinical trial of first or second-line treatment with bortezomib in patients with malignant pleural mesothelioma.
J Thorac Oncol
; 7(9): 1466-70, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22895144
16.
Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression.
PLoS One
; 7(12): e52753, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300762
17.
Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent.
Eur J Cancer
; 48(7): 1096-107, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22154545
18.
Response to chemotherapy is predictive in relation to longer overall survival in an individual patient combined-analysis with pleural mesothelioma.
Eur J Cancer
; 48(16): 2983-92, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704893
19.
Medicinal chemistry of combretastatin A4: present and future directions.
J Med Chem
; 49(11): 3033-44, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16722619
20.
MicroRNA regulation of core apoptosis pathways in cancer.
Eur J Cancer
; 47(2): 163-74, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145728