Detalhe da pesquisa
1.
Addendum: The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature
; 546(7659): 564, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640269
2.
Alzheimer disease neuropathology in a patient previously treated with aducanumab.
Acta Neuropathol
; 144(1): 143-153, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581440
3.
The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature
; 537(7618): 50-6, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27582220
4.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Am J Pathol
; 187(6): 1399-1412, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408124
5.
Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice.
J Neurosci
; 36(50): 12549-12558, 2016 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27810931
6.
Quantitative systems pharmacology model for Alzheimer's disease to predict the effect of aducanumab on brain amyloid.
CPT Pharmacometrics Syst Pharmacol
; 11(3): 362-372, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35029320
7.
Kinetic fingerprints differentiate the mechanisms of action of anti-Aß antibodies.
Nat Struct Mol Biol
; 27(12): 1125-1133, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989305
8.
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.
Nat Neurosci
; 23(12): 1580-1588, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199898
9.
Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-ß.
Sci Rep
; 8(1): 6412, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29686315
10.
Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease.
Neurobiol Aging
; 27(2): 270-7, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16399212
11.
BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aß isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease.
Neuropharmacology
; 103: 57-68, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26690893
12.
Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins--a role in nuclear localization.
Biochim Biophys Acta
; 1619(2): 167-76, 2003 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12527113
13.
Stereologic evidence for persistence of viable neurons in layer II of the entorhinal cortex and the CA1 field in Alzheimer disease.
J Neuropathol Exp Neurol
; 62(1): 55-67, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12528818
14.
Progressive degeneration of nonphosphorylated neurofilament protein-enriched pyramidal neurons predicts cognitive impairment in Alzheimer's disease: stereologic analysis of prefrontal cortex area 9.
J Comp Neurol
; 463(3): 281-302, 2003 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12820162
15.
Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
Am J Pathol
; 165(3): 987-95, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15331422