Detalhe da pesquisa
1.
Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.
EMBO J
; 40(22): e108125, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34617326
2.
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia.
Mol Cancer
; 21(1): 35, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35120522
3.
Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.
Nat Immunol
; 10(8): 880-8, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19561613
4.
Efficient fractionation and analysis of ribosome assembly intermediates in human cells.
RNA Biol
; 18(sup1): 182-197, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34530680
5.
T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.
Immunity
; 35(2): 208-22, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21820331
6.
YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
Am J Respir Crit Care Med
; 200(7): 888-899, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31166114
7.
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.
Proc Natl Acad Sci U S A
; 114(4): 764-769, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062691
8.
Focal accumulation of preribosomes outside the nucleolus during metaphase-anaphase in budding yeast.
RNA
; 23(9): 1432-1443, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28588079
9.
Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1.
EMBO J
; 38(5)2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30824546
10.
RHO GTPases in cancer: known facts, open questions, and therapeutic challenges.
Biochem Soc Trans
; 46(3): 741-760, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871878
11.
K-RasV14I recapitulates Noonan syndrome in mice.
Proc Natl Acad Sci U S A
; 111(46): 16395-400, 2014 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25359213
12.
The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.
PLoS Biol
; 11(7): e1001615, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935450
13.
Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation.
EMBO J
; 30(19): 3913-27, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21873980
14.
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
PLoS Genet
; 8(2): e1002458, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22319452
15.
Role of Src homology domain binding in signaling complexes assembled by the murid γ-herpesvirus M2 protein.
J Biol Chem
; 288(6): 3858-70, 2013 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23258536
16.
VAV3 mediates resistance to breast cancer endocrine therapy.
Breast Cancer Res
; 16(3): R53, 2014 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24886537
17.
Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.
Blood
; 120(4): 800-11, 2012 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22692505
18.
Intratumoral stages of metastatic cells: a synthesis of ontogeny, Rho/Rac GTPases, epithelial-mesenchymal transitions, and more.
Bioessays
; 34(9): 748-59, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22706877
19.
Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome.
Proc Natl Acad Sci U S A
; 108(12): 5015-20, 2011 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383153
20.
VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma.
Sci Rep
; 14(1): 4060, 2024 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38374399