Detalhe da pesquisa
1.
Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.
Circulation
; 141(17): 1384-1392, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160801
2.
Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor.
Br J Clin Pharmacol
; 79(5): 838-46, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25377242
3.
Reporting guidelines for population pharmacokinetic analyses.
J Pharmacokinet Pharmacodyn
; 42(3): 301-14, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25925797
4.
Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.
Neuroimage
; 99: 69-79, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844744
5.
Evaluation of the effect of naproxen on the pharmacokinetics and pharmacodynamics of apixaban.
Br J Clin Pharmacol
; 78(4): 877-85, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24697979
6.
Metabolism and clinical pharmacokinetics of 2-methyl-n-(2'-(pyrrolidinyl-1-ylsulfonyl)-n-[1,1'-biphenyl]-4-yl)propran-1-amine: insights into monoamine oxidase- and CYP-mediated disposition by integration of in vitro ADME tools.
Xenobiotica
; 44(5): 438-54, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24304147
7.
Population pharmacokinetic modeling of oral brepocitinib in healthy volunteers and patients with immuno-inflammatory diseases.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 551-562, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332554
8.
Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects.
Br J Clin Pharmacol
; 76(6): 908-16, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23488672
9.
Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects.
Br J Clin Pharmacol
; 76(5): 776-86, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23451769
10.
Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at risk of venous or arterial thrombotic disorder.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 500-512, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36861188
11.
The renal elimination of apixaban: the totality of data relating to the renal clearance of apixaban in patients with impaired renal function: response to Hellfritzsch et al.
Pharmacoepidemiol Drug Saf
; 26(5): 603-605, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444852
12.
Apixaban Use in Obese Patients: A Review of the Pharmacokinetic, Interventional, and Observational Study Data.
Am J Cardiovasc Drugs
; 22(6): 615-631, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570249
13.
Evaluation of the Effect of Abrocitinib on Drug Transporters by Integrated Use of Probe Drugs and Endogenous Biomarkers.
Clin Pharmacol Ther
; 112(3): 665-675, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35344588
14.
Population pharmacokinetics and exposure-response analyses of varenicline in adolescent smokers.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 769-781, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34062053
15.
Efficacy, Safety, and Exposure of Apixaban in Patients with High Body Weight or Obesity and Venous Thromboembolism: Insights from AMPLIFY.
Adv Ther
; 38(6): 3003-3018, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33890242
16.
Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review.
Clin Pharmacokinet
; 58(10): 1265-1279, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31089975
17.
The Effects of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Volunteers: A Single-Sequence Crossover Study.
Am J Cardiovasc Drugs
; 19(6): 561-567, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31030414
18.
Impact of censoring data below an arbitrary quantification limit on structural model misspecification.
J Pharmacokinet Pharmacodyn
; 35(1): 101-16, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17963024
19.
Regional Gastrointestinal Absorption of Apixaban in Healthy Subjects.
J Clin Pharmacol
; 58(7): 965-971, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29578609
20.
Population Pharmacokinetics of Apixaban in Subjects With Nonvalvular Atrial Fibrillation.
CPT Pharmacometrics Syst Pharmacol
; 7(11): 728-738, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30259707