Detalhe da pesquisa
1.
A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family.
Proc Natl Acad Sci U S A
; 120(49): e2305135120, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38032931
2.
Variable Penetrance and Expressivity of a Rare Pore Loss-of-Function Mutation (p.L889V) of Nav1.5 Channels in Three Spanish Families.
Int J Mol Sci
; 25(9)2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731905
3.
Reply to Benndorff and DiFrancesco: Reliable human HCN4 single-channel recordings using the cell-attached configuration in expression systems.
Proc Natl Acad Sci U S A
; 121(16): e2402992121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588416
4.
Zfhx3 Transcription Factor Represses the Expression of SCN5A Gene and Decreases Sodium Current Density (INa).
Int J Mol Sci
; 22(23)2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884836
5.
A Cantú syndrome mutation produces dual effects on KATP channels by disrupting ankyrin B regulation.
J Gen Physiol
; 155(1)2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36287534
6.
Empagliflozin and Dapagliflozin Increase Na+ and Inward Rectifier K+ Current Densities in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells (hiPSC-CMs).
Cells
; 11(23)2022 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36496967
7.
Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
Cardiovasc Res
; 118(4): 1046-1060, 2022 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576403
8.
The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval.
Sci Rep
; 10(1): 10707, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612162