Detalhe da pesquisa
1.
Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms endothelial cell biology.
Proc Natl Acad Sci U S A
; 120(3): e2214350120, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634146
2.
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8+ regulatory T cells.
Proc Natl Acad Sci U S A
; 118(21)2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006646
3.
Selective modifications of lactose and N-acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition.
Bioorg Med Chem
; 94: 117480, 2023 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774448
4.
An adipose tissue galectin controls endothelial cell function via preferential recognition of 3-fucosylated glycans.
FASEB J
; 34(1): 735-753, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914594
5.
Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.
Bioorg Med Chem
; 44: 116309, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293617
6.
Glycosylation-dependent galectin-receptor interactions promote Chlamydia trachomatis infection.
Proc Natl Acad Sci U S A
; 115(26): E6000-E6009, 2018 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891717
7.
Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?
Biochem Soc Trans
; 48(3): 1255-1268, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32597487
8.
Synthesis of N-acetylglucosamine and N-acetylallosamine resorcinarene-based multivalent ß-thio-glycoclusters: unexpected affinity of N-acetylallosamine ligands towards Wheat Germ Agglutinin.
Org Biomol Chem
; 18(35): 6853-6865, 2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856676
9.
Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells.
Biochim Biophys Acta
; 1860(10): 2255-68, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27130882
10.
Multivalent sialylation of ß-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography.
Glycoconj J
; 33(5): 809-18, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27306205
11.
Design and synthesis of hydrolytically stable multivalent ligands bearing thiodigalactoside analogues for peanut lectin and human galectin-3 binding.
J Org Chem
; 79(14): 6456-67, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937526
12.
Synthesis of divalent ligands of ß-thio- and ß-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase.
Beilstein J Org Chem
; 10: 3073-3086, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670976
13.
Escherichia coli ß-galactosidase inhibitors through modifications at the aglyconic moiety: experimental evidence of conformational distortion in the molecular recognition process.
Chemistry
; 19(13): 4262-70, 2013 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23424005
14.
Synthesis and biological activity of divalent ligands based on 3-deoxy-4-thiolactose, an isosteric analogue of lactose.
Org Biomol Chem
; 11(33): 5500-11, 2013 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23860803
15.
Targeting galectin-driven regulatory circuits in cancer and fibrosis.
Nat Rev Drug Discov
; 22(4): 295-316, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36759557
16.
Untangling Galectin-Mediated Circuits that Control Hypoxia-Driven Angiogenesis.
Methods Mol Biol
; 2442: 635-653, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320550
17.
A Dynamic Interplay of Circulating Extracellular Vesicles and Galectin-1 Reprograms Viral Latency during HIV-1 Infection.
mBio
; 13(4): e0061122, 2022 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943163
18.
Synthesis of multivalent glycoclusters from 1-thio-ß-D-galactose and their inhibitory activity against the ß-galactosidase from E. coli.
J Org Chem
; 76(9): 3064-77, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21446743
19.
[A functional platform to monitor SARS-CoV-2-specific T cell responses in vaccinated individuals and COVID-19 recovered patients]. / COVID-T: Una plataforma funcional para monitorear la respuesta de linfocitos T específicos de SARS-CoV-2 en individuos vacunados y recuperados de COVID-19.
Medicina (B Aires)
; 81(5): 683-687, 2021.
Artigo
em Espanhol
| MEDLINE | ID: mdl-34633939
20.
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2).
Cancer Lett
; 518: 72-81, 2021 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34144098