Detalhe da pesquisa
1.
Cancer-associated fibroblasts in pancreatic cancer: new subtypes, new markers, new targets.
J Pathol
; 257(4): 526-544, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35533046
2.
PKN2 deficiency leads both to prenatal 'congenital' cardiomyopathy and defective angiotensin II stress responses.
Biochem J
; 479(13): 1467-1486, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35730579
3.
The Future of Precision Oncology.
Int J Mol Sci
; 24(16)2023 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628794
4.
PKC and the control of localized signal dynamics.
Nat Rev Mol Cell Biol
; 11(2): 103-12, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20094051
5.
Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.
Carcinogenesis
; 35(2): 396-406, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072773
6.
Targets in the Tumour Matrisome to Promote Cancer Therapy Response.
Cancers (Basel)
; 16(10)2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791926
7.
Pseudokinase drug intervention: a potentially poisoned chalice.
Biochem Soc Trans
; 41(4): 1083-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863183
8.
mTORC2 targets AGC kinases through Sin1-dependent recruitment.
Biochem J
; 439(2): 287-97, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21806543
9.
Targeting the HER3 pseudokinase domain with small molecule inhibitors.
Methods Enzymol
; 667: 455-505, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35525551
10.
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion.
Cell Rep
; 38(4): 110227, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35081338
11.
Occupational hazards: allosteric regulation of protein kinases through the nucleotide-binding pocket.
Biochem Soc Trans
; 39(2): 472-6, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21428922
12.
Statins inhibit NK cell cytotoxicity by membrane raft depletion rather than inhibition of isoprenylation.
Atherosclerosis
; 191(2): 319-25, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16814295
13.
Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Oncotarget
; 8(49): 84685-84696, 2017 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29156676
14.
PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals.
Oncotarget
; 7(33): 53047-53063, 2016 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27344175
15.
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion.
Cell Rep
; 14(3): 440-448, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26774483
16.
Fluvastatin inhibits raft dependent Fcgamma receptor signalling in human monocytes.
Atherosclerosis
; 172(2): 219-28, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15019531
17.
Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease.
Atherosclerosis
; 175(2): 305-13, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15262187
18.
Differentiation of the human monocyte cell line, U937, with dibutyryl cyclicAMP induces the expression of the inhibitory Fc receptor, FcgammaRIIb.
Immunol Lett
; 83(3): 171-9, 2002 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12095707
19.
Towards specific inhibition of mTORC2.
Aging (Albany NY)
; 9(12): 2461-2462, 2017 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29232655
20.
PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.
Nat Struct Mol Biol
; 16(6): 624-30, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19465915