Detalhe da pesquisa
1.
Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.
Int J Mol Sci
; 23(9)2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563647
2.
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta.
Lab Invest
; 101(12): 1605-1617, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34462532
3.
Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor.
Tetrahedron Lett
; 60(3): 322-326, 2019 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30631216
4.
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.
Biochem Biophys Res Commun
; 499(4): 751-757, 2018 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604274
5.
C-O bond Formation in a Microfluidic Reactor: High Yield SNAr Substitution of Heteroaryl Chlorides.
Tetrahedron Lett
; 57(19): 2059-2062, 2016 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27152054
6.
A therapeutic small molecule lead enhances γ-oscillations and improves cognition/memory in Alzheimer's disease model mice.
bioRxiv
; 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106006
7.
Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate.
Elife
; 112022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36017995
8.
Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice.
Commun Med (Lond)
; 2: 112, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36082175
9.
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 70, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875010
10.
High-throughput screening identifies modulators of sarcospan that stabilize muscle cells and exhibit activity in the mouse model of Duchenne muscular dystrophy.
Skelet Muscle
; 10(1): 26, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32948250
11.
A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIß Signaling in Limb Girdle Muscular Dystrophy.
Cell Rep Med
; 1(7): 100122, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205074
12.
Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.
ACS Chem Biol
; 15(6): 1671-1684, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32352753
13.
Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage.
J Mol Biol
; 430(11): 1566-1576, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29649434
14.
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Sci Rep
; 8(1): 17574, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514854
15.
Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery.
J Drug Deliv
; 2017: 4759839, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28480080
16.
Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production.
Front Pharmacol
; 8: 46, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28261092
17.
Nanoscale Extracellular Vesicle Analysis in Alzheimer's Disease Diagnosis and Therapy.
Int J Alzheimers Dis
; 2016: 8053139, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27213078
18.
Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 108, 2021 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238327
19.
Netrin-1 Interrupts Amyloid-ß Amplification, Increases sAßPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 52(1): 223-42, 2016 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060954
20.
sAßPPα is a Potent Endogenous Inhibitor of BACE1.
J Alzheimers Dis
; 47(3): 545-55, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26401691