Detalhe da pesquisa
1.
Mechanisms controlling pancreatic islet cell function in insulin secretion.
Nat Rev Mol Cell Biol
; 22(2): 142-158, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398164
2.
The ubiquitination status of the glucagon receptor determines signal bias.
J Biol Chem
; 299(5): 104690, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037304
3.
Evaluating GIP and glucagon as key regulators of insulin secretion in the pancreatic islet.
Am J Physiol Endocrinol Metab
; 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38775725
4.
100 years of glucagon and 100 more.
Diabetologia
; 66(8): 1378-1394, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37367959
5.
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.
J Biol Chem
; 295(33): 11529-11541, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554468
6.
ß-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.
Am J Physiol Endocrinol Metab
; 319(4): E805-E813, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865009
7.
l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice.
Exp Physiol
; 105(2): 270-281, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802553
8.
Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.
Diabetologia
; 61(8): 1849-1855, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29858650
9.
GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells.
Peptides
; 175: 171179, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38360354
10.
Intra-islet α-cell Gs signaling promotes glucagon release.
Nat Commun
; 15(1): 5129, 2024 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38879678
11.
Characterization of genetic variants of GIPR reveals a contribution of ß-arrestin to metabolic phenotypes.
Nat Metab
; 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38871982
12.
GPCR Promiscuity Reshapes Islet Physiology.
Diabetes
; 72(9): 1180-1183, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603722
13.
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications.
Cell Metab
; 35(9): 1519-1529, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591245
14.
An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug.
Biomaterials
; 294: 121985, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630826
15.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
Nat Metab
; 5(6): 945-954, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277609
16.
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
iScience
; 26(5): 106748, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37216093
17.
Liver Fibroblast Growth Factor 21 (FGF21) is Required for the Full Anorectic Effect of the Glucagon-Like Peptide-1 Receptor Agonist Liraglutide in Male Mice fed High Carbohydrate Diets.
bioRxiv
; 2023 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711605
18.
Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets.
Mol Metab
; 72: 101718, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030441
19.
The past, present, and future physiology and pharmacology of glucagon.
Cell Metab
; 34(11): 1654-1674, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323234
20.
Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia.
PLoS One
; 17(6): e0270329, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749484