Detalhe da pesquisa
1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612233
2.
A small-molecule inhibitor of hepatitis C virus infectivity.
Antimicrob Agents Chemother
; 58(1): 386-96, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24165192
3.
Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873.
ACS Med Chem Lett
; 15(4): 546-554, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628802
4.
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Antimicrob Agents Chemother
; 57(2): 804-10, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23183437
5.
Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors.
Bioorg Med Chem Lett
; 22(13): 4288-92, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22664130
6.
Borabicyclo[3.3.2]decanes and the stereoselective asymmetric synthesis of 1,3-diol stereotriads from 1,3-diborylpropenes.
J Am Chem Soc
; 131(3): 1269-73, 2009 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19117388
7.
Highly enantioselective [4 + 2] cycloaddition reactions catalyzed by a chiral N-methyl-oxazaborolidinium cation.
Org Lett
; 10(15): 3271-3, 2008 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18582066
8.
N-propargylamides via the asymmetric michael addition of B-alkynyl-10-TMS-9- borabicyclo[3.3.2]decanes to N-acylimines.
Org Lett
; 8(15): 3331-4, 2006 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16836398
9.
Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection.
J Med Chem
; 57(5): 1893-901, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24144213
10.
Asymmetric synthesis of isomerically pure allenyl boranes from alkynyl boranes through a 1,2-insertion-1,3-borotropic rearrangement.
Angew Chem Int Ed Engl
; 46(3): 397-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17146820
11.
Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors.
ACS Med Chem Lett
; 2(10): 715-9, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900257
12.
Nonracemic 3 degrees-carbamines from the asymmetric allylboration of N-trimethylsilyl ketimines with B-allyl-10-phenyl-9-borabicyclo[3.3.2]decanes.
J Am Chem Soc
; 128(27): 8712-3, 2006 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16819848
13.
B-allyl-10-Ph-9-borabicyclo[3.3.2]decanes: strategically designed for the asymmetric allylboration of ketones.
J Am Chem Soc
; 127(33): 11572-3, 2005 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16104712
14.
Asymmetric allyl- and crotylboration with the robust, versatile, and recyclable 10-TMS-9-borabicyclo[3.3.2]decanes.
J Am Chem Soc
; 127(22): 8044-9, 2005 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15926828
15.
Highly enantioselective [2+2]-cycloaddition reactions catalyzed by a chiral aluminum bromide complex.
J Am Chem Soc
; 129(42): 12686-7, 2007 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17900126
16.
Chiral oxazaborolidine-aluminum bromide complexes are unusually powerful and effective catalysts for enantioselective Diels-Alder reactions.
J Am Chem Soc
; 129(6): 1498-9, 2007 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17283985