[Blood groups of the ABO system and survival rate in gynecologic tumors]. / Gruppi sanguigni del sistema ABO e sopravvivenza nei tumori ginecologici.

A retrospective analysis of 968 women affected by gynecological tumors was conducted to assess the existence of a difference in survival between patients with different blood groups. Data are presented on 237 cases of endometrial cancer, 92 cases of ovarian cancer and 639 cases of invasive cervix cancer, detailing their ABO blood antigenic phenotypes, the stage of neoplasia and the treatment received. With regard to endometrial cancer, a sensibly better 5-year and 10-year survival is associated with blood group 0 if compared with blood group A. This finding is more evident when 5-year survival is considered among patients affected by ovarian cancer. With regard to cervical cancer, analysis showed that a little better than 5-year survival is associated with 0 blood phenotype; on the contrary, when a 10-year or longer survival is considered, a better survival is associated with A blood phenotype. The present study confirms evidence of an association between the A blood group and gynecological tumors. Endometrial and ovarian cancer occur more frequently in women with blood type A than in those with the other blood types, moreover, in the same tumors blood group A is associated with a poor prognosis. The possible reason for these findings are discussed with detailed regard to the possible biological importance that, at present, is conferred to the ABO group system in the complex activities of the immune system.

[Measurement of radon concentrations in schools at 2 communities of Puglia and oncologic risk]. / Indagine sulle concentrazioni di radon nelle scuole di due comuni pugliesi e rischio oncologico.

Measurements of radon's concentration have been effected in the schools of two communes of Puglia: Polignano and Valenzano. The average concentration of radon, based on the prospecting effected in the research period (spring/summer 1997), appeared, for both communes, lower than national average (75 Bq/m3). However, these average concentrations is below estimated caused of the limitation of the research period, owing to organization only at the period spring/summer. In fact, by the extrapolation applying a right factor of conversion, of the "winter" average concentrations from that average calculated during the research period (considering the evident limits of such procedure) we obtain, respectively, for both schools of Polignano and Valenzano, an average concentrations about of 75 Bq/m3 e 103 Bq/m3. The research shows the existence of a correlation among the obtained results and two important factors: the buildings materials utilized and the geological conformation of the subsoil; in particular, the buildings having main wall (tufa) or built by mixed materials (cement, bricks and tufa) measured the highest radon concentrations. Nevertheless, the absolute risk to develop a pulmonary tumour due to the radon exposition, limitedly for the population of the common of Valenzano, appears lightly superior in respect of the national risk (6 cases on 100,000 fellows) resulted about 8.5 case on 100,000 fellows.

[Indoor radon pollution in houses in the Apulian Region of Italy and evaluation of the probability of lung cancer in the population]. / Contaminazione da radon indoor nelle abitazioni pugliesi e valutazione della probabilità di insorgenza di tumore polmonare nella popolazione residente.

BACKGROUND: Radon-222 is a gaseous radioactive chemical which can be transformed into other radioactive chemicals, defined as "products of decay" or "radon's daughter". The modality of radon penetration into the buildings depends on the convection motion created in the ground, which suck it back, so causing the penetration. The principal effect on human health is the increase risk of lung cancer, in proportion to the concentration and the time people spend indoors with exposure to radon. OBJECTIVES: The study proposed to estimate the expected cases of radon-induced lung cancer in the population of Apulia due to contamination by indoor radon. METHODS: The study used the data obtained in a national survey made by ANPA (National Environmental Protection Agency) and ISS (High Health Institute), with the collaboration of the Regional Reference Centres for the Control of Environmental Radioactivity (CRR). In the Apulia Region 310 families (5000 nationwide) were involved, which were selected so as to constitute a representative sample both of the region and the country. Appropriate instruments for the measurement of mean concentrations of indoor radon (passive nuclear trace monitors were installed in the homes of the sample families in two different periods of year). We evaluated the variations of indoor radon concentration in the houses during spring-summer and autumn-winter periods, observing a predictable increase in the latter period. We assessed concentrations in relation to: 1. architectural features and location, 2. construction year, 3. building material, 4. presence of windows. RESULTS: We found higher contamination in the oldest non-cement buildings and on the lower floors. In Lecce and Castrì di Lecce we found a mean radon concentration higher than the national and the regional mean, which is equivalent to annual exposure of 0.54 and 0.46 WLM respectively. For these levels we estimated that the expected cases of radon-induced lung cancer will be 1.5 in Lecce and 1.3 in Castrì per 10,000 inhabitants. CONCLUSION: The results of our investigations confirm that indoor radon pollution is a significant problem as it is one of the main causes of lung cancer. Hence, precautionary measures to reduce as much as possible exposure to indoor radon are highly recommended.

[Ionizing radiation and video computer terminals]. / Radiazioni ionizzanti e video terminali.

VDTs are more frequently being used and, therefore have given rise to the problem of security among operators exposed to possible X-ray emissions. The authors report the results of a dosimetric investigation, carried out through TLD CaF2:Dy on X-ray exposure levels close to video display terminals of a data processing center. After testing the exposure percentage values and the measurements adjusted to one-year basis, the authors report that the value are generally similar to those existing in the environment even though significant values have been found in a few cases.