Detalhe da pesquisa
1.
Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody.
J Biol Chem
; 285(46): 36149-57, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833723
2.
Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases.
J Biol Chem
; 284(41): 28093-28103, 2009 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679662
3.
Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Trial in Patients Hospitalized with Heart Failure (HORIZON-HF) trial.
Am Heart J
; 157(6): 1035-41, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19464414
4.
OXavidin for tissue targeting biotinylated therapeutics.
J Biomed Biotechnol
; 2009: 921434, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-20130784
5.
Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.
Mol Cancer Ther
; 7(7): 2051-9, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18645015
6.
Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968.
Eur J Cancer
; 44(9): 1332-40, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18445521
7.
Olanzapine (LY170053, 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine), but not the novel atypical antipsychotic ST2472 (9-piperazin-1-ylpyrrolo[2,1-b][1,3]benzothiazepine), chronic administration induces weight gain, hyperphagia, and metabolic dysregulation in mice.
J Pharmacol Exp Ther
; 326(3): 905-11, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18567835
8.
Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88.
J Med Chem
; 51(5): 1189-202, 2008 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18275134
9.
Synthesis and biological activity of fluorinated combretastatin analogues.
J Med Chem
; 51(9): 2708-21, 2008 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18396857
10.
Novel substituted aminoalkylguanidines as potential antihyperglycemic and food intake-reducing agents.
J Med Chem
; 51(11): 3073-6, 2008 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18465847
11.
Efficacy of a nanocochleate-encapsulated 3,5-diaryl-s-triazole derivative in a murine model of graft-versus-host disease.
Transplantation
; 86(1): 171-5, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18622296
12.
Sympathomimetic inefficiency in restoring contractility in the acute or chronic beta-blocker-treated ischaemic heart: comparison with a new agent.
Eur J Heart Fail
; 10(10): 990-6, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18693136
13.
Intraoperative avidination for radionuclide therapy: a prospective new development to accelerate radiotherapy in breast cancer.
Clin Cancer Res
; 13(18 Pt 2): 5646s-5651s, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17875802
14.
Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.
J Leukoc Biol
; 82(4): 801-10, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548806
15.
2-Aminotetraline derivative protects from ischemia/reperfusion brain injury with a broad therapeutic window.
Neuropsychopharmacology
; 32(6): 1302-11, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17119539
16.
Hemodynamic properties of a new-generation positive luso-inotropic agent for the acute treatment of advanced heart failure.
Am J Cardiol
; 99(2A): 41A-46A, 2007 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17239704
17.
Istaroxime: a new luso-inotropic agent for heart failure.
Am J Cardiol
; 99(2A): 33A-40A, 2007 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17239702
18.
A phase 1-2 dose-escalating study evaluating the safety and tolerability of istaroxime and specific effects on electrocardiographic and hemodynamic parameters in patients with chronic heart failure with reduced systolic function.
Am J Cardiol
; 99(2A): 47A-56A, 2007 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17239705
19.
The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism.
Biochem Pharmacol
; 73(5): 643-55, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17150196
20.
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.
Biochem Pharmacol
; 73(5): 656-64, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17169332