Detalhe da pesquisa
1.
Development of an easy-to-set-up multiple heart-cutting achiral-chiral LC-LC method for the analysis of branched-chain amino acids in commercial tablets.
Electrophoresis
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477690
2.
Estimating the hydrophobicity extent of molecular fragments using reversed-phase liquid chromatography.
J Sep Sci
; 46(18): e2300346, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37438993
3.
Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency.
Int J Mol Sci
; 24(6)2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982608
4.
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls.
Int J Mol Sci
; 23(7)2022 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409342
5.
Environmentally Sustainable Achiral and Chiral Chromatographic Analysis of Amino Acids in Food Supplements.
Molecules
; 27(22)2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36431824
6.
Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands.
Org Biomol Chem
; 19(24): 5403-5412, 2021 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34056641
7.
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol.
J Chem Inf Model
; 60(3): 1737-1748, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32045233
8.
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres.
Bioorg Med Chem
; 28(22): 115731, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007550
9.
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers.
Bioorg Chem
; 99: 103777, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32222619
10.
Binding modes identification through molecular dynamic simulations: A case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase.
J Sep Sci
; 43(9-10): 1728-1736, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112671
11.
Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines.
Molecules
; 25(3)2020 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024219
12.
Last ten years (2008-2018) of chiral ligand-exchange chromatography in HPLC: An updated review.
J Sep Sci
; 42(1): 21-37, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30152147
13.
Exploring the enantiorecognition mechanism of Cinchona alkaloid-based zwitterionic chiral stationary phases and the basic trans-paroxetine enantiomers.
J Sep Sci
; 41(6): 1199-1207, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29160617
14.
Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX-2 inhibitory activity.
Chirality
; 29(9): 536-540, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28677874
15.
Quinine-Based Zwitterionic Chiral Stationary Phase as a Complementary Tool for Peptide Analysis: Mobile Phase Effects on Enantio- and Stereoselectivity of Underivatized Oligopeptides.
Chirality
; 28(1): 5-16, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26483276
16.
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy.
Biochim Biophys Acta
; 1844(10): 1765-72, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25062913
17.
Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.
Bioorg Med Chem Lett
; 24(15): 3422-5, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24948563
18.
Ketoprofen enantioseparation with a Cinchona alkaloid based stationary phase: enantiorecognition mechanism and release studies.
J Sep Sci
; 37(19): 2696-703, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25044910
19.
Discovery and Structure-Activity Relationships of Novel ssDAF-12 Receptor Modulators.
J Med Chem
; 67(5): 4150-4169, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417155
20.
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: role of the chirality on the biological activity.
Bioorg Med Chem
; 21(13): 3780-9, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23684233