Detalhe da pesquisa
1.
Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells.
Retrovirology
; 20(1): 5, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37127613
2.
Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex.
Biochemistry
; 61(18): 1974-1987, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070615
3.
DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages.
EMBO J
; 37(1): 50-62, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084722
4.
Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers.
Biochemistry
; 60(21): 1682-1698, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33988981
5.
Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
PLoS Pathog
; 11(10): e1005194, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431200
6.
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun
; 15(1): 3775, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710701
7.
Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun
; 11(1): 3165, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32576829