Detalhe da pesquisa
1.
A peptoid-based inhibitor of protein arginine methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells.
J Biol Chem
; 298(8): 102205, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764172
2.
Histone H4-based peptoids are inhibitors of protein arginine methyltransferase 1 (PRMT1).
Biochem J
; 477(16): 2971-2980, 2020 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32716034
3.
The development and characterization of a chemical probe targeting PRMT1 over PRMT5.
Bioorg Med Chem
; 27(1): 224-229, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529151
4.
Inhibiting protein arginine deiminases has antioxidant consequences.
J Pharmacol Exp Ther
; 353(1): 64-70, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25635139
5.
Synthesis and evaluation of 2-ethynyl-adenosine-5'-triphosphate as a chemical reporter for protein AMPylation.
Org Biomol Chem
; 13(31): 8550-5, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26173047
6.
Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases.
Bioorg Med Chem
; 23(9): 2159-67, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25819331
7.
Atomic force microscopy characterization and lithography of Cu-ligated mercaptoalkanoic acid "molecular ruler" multilayers.
Langmuir
; 30(25): 7447-55, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24897619
8.
Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases.
Bioorg Med Chem
; 22(17): 4602-8, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25127464
9.
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.
PLoS Genet
; 7(6): e1002112, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21655091
10.
N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.
J Immunol
; 186(7): 4396-404, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21346230
11.
Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability.
Dev Biol
; 355(2): 205-14, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21539830
12.
Potential role for PADI-mediated histone citrullination in preimplantation development.
BMC Dev Biol
; 12: 19, 2012 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22712504
13.
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.
BMC Cancer
; 12: 500, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23110523
14.
Protein arginine deiminase 4: a target for an epigenetic cancer therapy.
Cell Mol Life Sci
; 68(4): 709-20, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20706768
15.
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.
Am J Physiol Gastrointest Liver Physiol
; 300(6): G929-38, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415415
16.
Mechanistic studies of agmatine deiminase from multiple bacterial species.
Biochemistry
; 49(43): 9413-23, 2010 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20939536
17.
Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.
Biochemistry
; 49(23): 4852-63, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20469888
18.
Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation.
Chembiochem
; 11(2): 161-5, 2010 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20014086
19.
Characterization and inactivation of an agmatine deiminase from Helicobacter pylori.
Bioorg Chem
; 38(2): 62-73, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20036411
20.
An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4).
Tetrahedron Lett
; 49(28): 4383-4385, 2008 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19587776