Detalhe da pesquisa
1.
Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity.
Antimicrob Agents Chemother
; 65(3)2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318019
2.
Design, synthesis, and evaluation of substrate - analogue inhibitors of Trypanosoma cruzi ribose 5-phosphate isomerase type B.
Bioorg Med Chem Lett
; 32: 127723, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33249135
3.
Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla.
Exp Parasitol
; 135(3): 611-22, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24090569
4.
Update on relevant trypanosome peptidases: Validated targets and future challenges.
Biochim Biophys Acta Proteins Proteom
; 1869(2): 140577, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271348
5.
Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes.
PLoS Negl Trop Dis
; 13(7): e0007560, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31329594
6.
DNA-damage inducible protein 1 is a conserved metacaspase substrate that is cleaved and further destabilized in yeast under specific metabolic conditions.
FEBS J
; 285(6): 1097-1110, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363267
7.
Author Correction: Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes.
Sci Rep
; 8(1): 8743, 2018 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29867193
8.
Substrate specificity profiling of M32 metallocarboxypeptidases from Trypanosoma cruzi and Trypanosoma brucei.
Mol Biochem Parasitol
; 219: 10-16, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29246805
9.
Structure, kinetic characterization and subcellular localization of the two ribulose 5-phosphate epimerase isoenzymes from Trypanosoma cruzi.
PLoS One
; 12(2): e0172405, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207833
10.
Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes.
Sci Rep
; 7(1): 12073, 2017 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935948
11.
The glucose-6-phosphate dehydrogenase from Trypanosoma cruzi: its role in the defense of the parasite against oxidative stress.
Mol Biochem Parasitol
; 149(2): 170-81, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16828178
12.
The trypanosomiases.
Lancet
; 362(9394): 1469-80, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14602444
13.
Transketolase from Leishmania mexicana has a dual subcellular localization.
Biochem J
; 382(Pt 2): 759-67, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15149284
14.
Biosynthesis of SUMOylated Proteins in Bacteria Using the Trypanosoma brucei Enzymatic System.
PLoS One
; 10(8): e0134950, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26258470
15.
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
Mol Biochem Parasitol
; 133(2): 197-207, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14698432
16.
Specific cleavage sites on human IgG subclasses by cruzipain, the major cysteine proteinase from Trypanosoma cruzi.
Mol Biochem Parasitol
; 130(1): 23-9, 2003 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-14550893
17.
Purification, cloning, and expression of the mitochondrial malate dehydrogenase (mMDH) from protoscolices of Echinococcus granulosus.
Mol Biochem Parasitol
; 137(2): 207-14, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15383291
18.
Characterization of a lysosomal serine carboxypeptidase from Trypanosoma cruzi.
Mol Biochem Parasitol
; 131(1): 11-23, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12967708
19.
Pentose phosphate metabolism in Leishmania mexicana.
Mol Biochem Parasitol
; 130(2): 117-25, 2003 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12946848
20.
Proteinases of Trypanosoma cruzi: patential targets for the chemotherapy of Changas desease.
Curr Top Med Chem
; 2(11): 1261-71, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12171584