Detalhe da pesquisa
1.
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy.
Toxicol Appl Pharmacol
; 434: 115797, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780725
2.
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta.
Arch Toxicol
; 94(11): 3799-3817, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915249
3.
Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics.
Drug Metab Dispos
; 47(9): 954-960, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31266750
4.
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.
Drug Metab Dispos
; 47(7): 699-709, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068367
5.
The inhibitory effect of antiretroviral drugs on the L-carnitine uptake in human placenta.
Toxicol Appl Pharmacol
; 368: 18-25, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735677
6.
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes.
Mol Pharm
; 16(11): 4436-4450, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31633365
7.
Equilibrative Nucleoside Transporter 1 (ENT1, SLC29A1) Facilitates Transfer of the Antiretroviral Drug Abacavir across the Placenta.
Drug Metab Dispos
; 46(11): 1817-1826, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30097436
8.
MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption.
Antimicrob Agents Chemother
; 61(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28696229
9.
Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters.
Xenobiotica
; 47(1): 77-85, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27052107
10.
Role of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine.
Antimicrob Agents Chemother
; 60(9): 5563-72, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401571
11.
Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs).
Xenobiotica
; 46(5): 416-23, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26364927
12.
Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.
Biopharm Drug Dispos
; 37(1): 28-38, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390406
13.
Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms.
Toxicol Appl Pharmacol
; 285(1): 12-22, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25771127
14.
Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms.
Infect Immun
; 81(3): 629-35, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264049
15.
Organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter in the placenta and fetal tissues: expression profile and fetus protective role at different stages of gestation.
Biol Reprod
; 88(3): 55, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303678
16.
Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone.
Pharmacol Res
; 65(3): 312-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22173067
17.
ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia.
Biomed Pharmacother
; 150: 112962, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35462331
18.
Fetoprotective activity of breast cancer resistance protein (BCRP, ABCG2): expression and function throughout pregnancy.
Drug Metab Rev
; 43(1): 53-68, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20854129
19.
Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta.
Biomed Pharmacother
; 129: 110506, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32768979
20.
Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors.
Cancers (Basel)
; 12(6)2020 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32560251