Detalhe da pesquisa
1.
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
J Transl Med
; 22(1): 292, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38504345
2.
Phase Ib study evaluating safety and clinical activity of the anti-HER3 antibody lumretuzumab combined with the anti-HER2 antibody pertuzumab and paclitaxel in HER3-positive, HER2-low metastatic breast cancer.
Invest New Drugs
; 36(5): 848-859, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29349598
3.
Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells.
Proc Natl Acad Sci U S A
; 109(8): 3006-11, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22315398
4.
Comprehensive analysis of fibroblast activation protein expression across 23 tumor indications: insights for biomarker development in cancer immunotherapies.
Front Immunol
; 15: 1352615, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38558814
5.
Spontaneous, naturally occurring cancers in non-human primates as a translational model for cancer immunotherapy.
J Immunother Cancer
; 11(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36593067
6.
A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors.
Sci Transl Med
; 15(695): eabp9229, 2023 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37163618
7.
A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2.
Hum Mutat
; 33(6): 998-1009, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22473970
8.
SUnSET, a nonradioactive method to monitor protein synthesis.
Nat Methods
; 6(4): 275-7, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19305406
9.
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells.
Proc Natl Acad Sci U S A
; 106(8): 2735-40, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19193853
10.
MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.
Proc Natl Acad Sci U S A
; 105(9): 3491-6, 2008 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18305173
11.
5' Region Large Genomic Rearrangements in the BRCA1 Gene in French Families: Identification of a Tandem Triplication and Nine Distinct Deletions with Five Recurrent Breakpoints.
Cancers (Basel)
; 13(13)2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34202044
12.
Genetic modification of murine dendritic cells by RNA transfection.
Methods Mol Biol
; 531: 145-56, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19347316
13.
Translation and evaluation of a pre-clinical 5-protein response prediction signature in a breast cancer phase Ib clinical trial.
PLoS One
; 14(3): e0213892, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30897176
14.
A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer.
ESMO Open
; 4(4): e000532, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31423336
15.
Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Sci Transl Med
; 11(496)2019 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31189721
16.
Direct estrogen receptor (ER) / HER family crosstalk mediating sensitivity to lumretuzumab and pertuzumab in ER+ breast cancer.
PLoS One
; 12(5): e0177331, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493933
17.
Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity.
Clin Cancer Res
; 23(18): 5406-5415, 2017 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600476
18.
First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors.
Clin Cancer Res
; 22(4): 877-85, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26463709
19.
Multiple recent horizontal transfers of a large genomic region in cheese making fungi.
Nat Commun
; 5: 2876, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24407037
20.
Direct visualization of the highly polymorphic RNU2 locus in proximity to the BRCA1 gene.
PLoS One
; 8(10): e76054, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24146815