Detalhe da pesquisa
1.
Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell
; 175(4): 1045-1058.e16, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388443
2.
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome.
J Med Genet
; 61(5): 490-501, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296633
3.
Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res
; 51(10): 5255-5270, 2023 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37115000
4.
Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase.
Hum Mol Genet
; 25(11): 2234-2244, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27005423
5.
Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem J
; 474(22): 3747-3761, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963344
6.
Reducing hyperglucagonaemia in type 2 diabetes using low-dose glibenclamide: Results of the LEGEND-A pilot study.
Diabetes Obes Metab
; 24(8): 1671-1675, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35491519
7.
Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking.
J Biol Chem
; 290(49): 29167-77, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26483544
8.
Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A.
BMC Infect Dis
; 14: 660, 2014 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25466778
9.
Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
Structure
; 32(4): 453-466.e6, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38309262
10.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
PLoS One
; 19(2): e0293548, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359047
11.
An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition.
Nat Commun
; 14(1): 1545, 2023 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36941262
12.
Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Sci Adv
; 9(39): eadg8229, 2023 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774028
13.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
bioRxiv
; 2023 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37547005
14.
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells.
Nat Chem
; 14(3): 284-293, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35145246
15.
High-performance liquid chromatography separation and intact mass analysis of detergent-solubilized integral membrane proteins.
Anal Biochem
; 410(2): 272-80, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21093405
16.
Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting.
Commun Biol
; 4(1): 934, 2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34345007
17.
Structural Insights into Notum Covalent Inhibition.
J Med Chem
; 64(15): 11354-11363, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34292747
18.
An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells.
Chem Sci
; 11(33): 8936-8944, 2020 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33815738
19.
Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity.
J Clin Invest
; 130(3): 1116-1121, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31821173
20.
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition.
Nat Commun
; 9(1): 2261, 2018 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891918